Evidence map›Paper›PMID 36152755›Full record

ArticleJournal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus2022

Quantitative comparison of blood vessel changes after treatment of retinopathy of prematurity with laser versus bevacizumab.

Weiliang Wang, Gloria J Hong, Sandra S Stinnett, Sharon F Freedman, David K Wallace, S Grace Prakalapakorn

Open access · greenAbstract readCase Reports
In one paragraph

Article in Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Weiliang WangDuke-National University of Singapore Medical School, Singapore.
Gloria J HongDepartment of Ophthalmology, Duke University Medical Center, Durham, North Carolina.
Sandra S StinnettDepartment of Ophthalmology, Duke University Medical Center, Durham, North Carolina.
Sharon F FreedmanDepartment of Ophthalmology, Duke University Medical Center, Durham, North Carolina; Department of Pediatrics, Duke University Medical Center, Durham, North Carolina.
David K WallaceDepartment of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana.
S Grace PrakalapakornDepartment of Ophthalmology, Duke University Medical Center, Durham, North Carolina; Department of Pediatrics, Duke University Medical Center, Durham, North Carolina. Electronic address: grace.prakalapakorn@duke.edu.
Duke Medical Center · USIndiana University School of MedicineNational University of Singapore · SG

Funding

Pediatric Eye Disease Investigator Group Coordinating CenterU10EY011751 · NEI · JAEB CENTER FOR HEALTH RESEARCH, INC. · PI KRAKER, RAYMOND · 1997 to 2018
$75.2M
Pediatric Eye Disease Investigator Group NetworkUG1EY011751 · NEI · JAEB CENTER FOR HEALTH RESEARCH, INC. · PI Raymond Kraker, Stacy Pineles · 2019 to 2026
$53.7M
Evaluating a non-contact fundus camera for retinopathy of prematurity screeningK23EY024268 · NEI · DUKE UNIVERSITY · PI PRAKALAPAKORN, SASAPIN GRACE · 2014 to 2016
$638k
NEI NIH HHS K23 EY024268NEI NIH HHS U10 EY011751NEI NIH HHS UG1 EY011751
6 · The paper itself

Abstract

Current therapies for treatment-indicated (type 1) retinopathy of prematurity mainly consist of laser photocoagulation and intravitreal anti-vascular endothelial growth factor (eg, bevacizumab) injection. The first visible signs of acute-phase regression are typically vascular, including decreased plus disease. Using a semiautomated computer program, we quantitatively compared posterior pole vascular changes following treatment with laser versus bevacizumab and found that in the first month following treatment, vascular dilation and tortuosity significantly decreased following either treatment modality, but tortuosity decreased earlier and faster after bevacizumab.

Indexed as

Retinopathy of PrematurityAngiogenesis InhibitorsBevacizumabCombined Modality TherapyGestational AgeHumansInfant, NewbornIntravitreal InjectionsLaser CoagulationLasersVascular Endothelial Growth Factor AAngiogenesis InhibitorsBevacizumabVascular Endothelial Growth Factor A

Identifiers

PMID36152755
PMCPMC9772077
OpenAlexW4296640241

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.