Evidence map›Paper›PMID 36152404›Full record

ArticleDrug and alcohol dependence2022

Characteristics and correlates of fentanyl preferences among people with opioid use disorder.

Karli R Hochstatter, Mishka Terplan, Shannon Gwin Mitchell, Robert P Schwartz, Kristi Dusek, Kim Wireman, Jan Gryczynski

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Karli R HochstatterFriends Research Institute, 1040 Park Avenue, Suite 103, Baltimore, MD 21201, USA. Electronic address: khochstatter@friendsresearch.org.
Mishka TerplanFriends Research Institute, 1040 Park Avenue, Suite 103, Baltimore, MD 21201, USA.
Shannon Gwin MitchellFriends Research Institute, 1040 Park Avenue, Suite 103, Baltimore, MD 21201, USA.
Robert P SchwartzFriends Research Institute, 1040 Park Avenue, Suite 103, Baltimore, MD 21201, USA.
Kristi DusekFriends Research Institute, 1040 Park Avenue, Suite 103, Baltimore, MD 21201, USA.
Kim WiremanPowell Recovery Center, 14S. Broadway, Baltimore, MD 21231, USA.
Jan GryczynskiFriends Research Institute, 1040 Park Avenue, Suite 103, Baltimore, MD 21201, USA.

Funding

The Lifespan/Brown Criminal Justice Research Program on Substance Use and HIVR25DA037190 · NIDA · MIRIAM HOSPITAL · PI CURT G BECKWITH · 2014 to 2026
$3.5M
People Preferring Fentanyl (PPF): Characteristics, Outcomes, and PerspectivesR21DA047580 · NIDA · FRIENDS RESEARCH INSTITUTE, INC. · PI GRYCZYNSKI, JAN · 2019 to 2020
$440k
NIDA NIH HHS R21 DA047580NIDA NIH HHS R25 DA037190
6 · The paper itself

Abstract

objectivesFentanyl has come to dominate the U.S. illicit opioid supply. We aimed to characterize and examine correlates of preferences for fentanyl vs. other opioids among individuals starting OUD treatment.

methodsWe interviewed 250 adults initiating buprenorphine treatment with positive fentanyl toxicology at intake. We characterized opioid preferences and examined bivariate associations between opioid preference (preference for heroin, fentanyl, heroin-fentanyl mix, or other opioid) and sociodemographic characteristics, psychosocial factors, and substance use behaviors. We then used multinomial logistic regression to examine factors independently associated with fentanyl preferences.

resultsOver half (52.0 %) of participants preferred fentanyl (21.2 % fentanyl alone, 30.8 % heroin-fentanyl mix). In bivariate comparisons, participants who preferred fentanyl were a higher acuity group with respect to risks and problems in general. In the multinomial logistic regression, people who preferred fentanyl, either alone or mixed with heroin, used non-prescribed buprenorphine less in the 30 days preceding treatment entry compared to people who preferred heroin or other opioids (RRR

conclusionsMany people with OUD report preferring fentanyl. People who express preference for fentanyl differ substantively from those with other opioid preferences, and may be at elevated risk for poor health outcomes. Understanding preferences surrounding fentanyl could inform treatment and harm reduction interventions.

Indexed as

BuprenorphineDrug OverdoseOpioid-Related DisordersAdultAnalgesics, OpioidFentanylHeroinHumansAnalgesics, OpioidBuprenorphineFentanylHeroinBuprenorphine treatmentFentanyl preferenceOpioid use disorder

Identifiers

PMID36152404
PMCPMC9616126

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.