Evidence map›Paper›PMID 36152292›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2023

Extracellular Vesicle Molecular Profiling for Diagnostic Purposes: An Application of Phage Display Technology.

Stella Garcia Colombarolli, Alberto Vitali, Francesca Sciandra

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Engineered EVs designed to target diseases of the CNS.Journal of controlled release : official journal of the Controlled Release Society · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Stella Garcia ColombarolliNational Research Council of Italy, Istituto di Scienze e Tecnologie Chimiche (SCITEC-CNR), Rome, Italy. stellacolombarolli29@gmail.com.
Alberto VitaliNational Research Council of Italy, Istituto di Scienze e Tecnologie Chimiche (SCITEC-CNR), Rome, Italy.
Francesca SciandraNational Research Council of Italy, Istituto di Scienze e Tecnologie Chimiche (SCITEC-CNR), Rome, Italy.
National Research Council · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phage display is a molecular biology cloning technique that allows the expression of genes of interest along with the phage surface protein. The technique described for the following method used a genomic library for the expression of peptides composed of 12 amino acids, with the objective of selecting peptides which presented specific affinity to the molecules of interest. As a target, purified extracellular vesicles from cell cultures of cells 5637 and RT4 were chosen, which in turn have enormous application and can help to understand the functioning of bladder cancer, allowing the development of new vaccines, drugs, therapies, and diagnoses.

Indexed as

BacteriophagesExtracellular VesiclesVaccinesAmino AcidsMembrane ProteinsPeptide LibraryPeptidesTechnologyAmino AcidsMembrane ProteinsPeptide LibraryPeptidesVaccinesExtracellular vesiclesin vitro peptide selectionPhage display techniqueProtein targetSpecific peptides discovery

Identifiers

PMID36152292
OpenAlexW4297174695

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.