Evidence map›Paper›PMID 36152289›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2023

Peptide Microarrays for Flavivirus Diagnosis.

Stella Garcia Colombarolli, Izabella Cristina Andrade Batista, Naiara Clemente Tavares, Eneida Santos de Oliveira, Camila Sales Nascimento, Philip Louis Felgner, Rafael Ramiro de Assis, Carlos Eduardo Calzavara-Silva

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Article in Methods in molecular biology (Clifton, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Stella Garcia ColombarolliNational Research Council of Italy, Istituto di Scienze e Tecnologie Chimiche (SCITEC-CNR), Rome, Italy.
Izabella Cristina Andrade BatistaLaboratório de Imunologia Celular e Molecular, Instituto Rene Rachou, Fiocruz, MG, Brazil.
Naiara Clemente TavaresLaboratório de Imunologia Celular e Molecular, Instituto Rene Rachou, Fiocruz, MG, Brazil.
Eneida Santos de OliveiraLaboratório de Imunologia Celular e Molecular, Instituto Rene Rachou, Fiocruz, MG, Brazil.
Camila Sales NascimentoLaboratório de Imunologia Celular e Molecular, Instituto Rene Rachou, Fiocruz, MG, Brazil.
Philip Louis FelgnerVaccine Research and Development Center, Department of Physiology, University of California, Irvine, CA, USA.
Rafael Ramiro de AssisVaccine Research and Development Center, Department of Physiology, University of California, Irvine, CA, USA.
Carlos Eduardo Calzavara-SilvaLaboratório de Imunologia Celular e Molecular, Instituto Rene Rachou, Fiocruz, MG, Brazil. carlos.calzavara@fiocruz.br.
University of California, Irvine · USNational Research Council · ITPrefeitura Municipal de Belo Horizonte · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Flavivirus are the most alarming prevalent viruses worldwide due to its vast impact on public health. Most early symptoms of diseases caused by Flavivirus are similar among each other and to other febrile illnesses making the clinical differential diagnosis challenging. In addition, due to cross-reactivity and a relatively limited persistence of viral RNA in infected individuals, the current available diagnosis strategies fail to efficiently provide a differential viral identification. In this context, virus-specific tests are essential to improve patient care, as well as to facilitate disease surveillance and the effective control of transmission. Here, we describe the use of protein microarrays as an effective tool for screening peptides differentially recognized by anti-Yellow Fever virus antibodies induced by vaccination or by natural viral infection.

Indexed as

FlavivirusAntibodies, ViralCross ReactionsHumansPeptidesRNA, ViralAntibodies, ViralPeptidesRNA, ViralDifferential diagnosisFlavivirusPeptide microarrayYellow Fever virus.

Identifiers

PMID36152289
OpenAlexW4297174607

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.