Evidence map›Paper›PMID 36152263›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2023

Prussian Blue Staining to Visualize Iron Oxide Nanoparticles.

Valeria Bitonto, Francesca Garello, Arnaud Scherberich, Miriam Filippi

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

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  6. Novel FeInternational journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Valeria BitontoDepartment of Molecular Biotechnology and Health Sciences, University of Turin, Torino, Italy.
Francesca GarelloDepartment of Molecular Biotechnology and Health Sciences, University of Turin, Torino, Italy.
Arnaud ScherberichDepartment of Biomedicine, University and University Hospital of Basel, Basel, Switzerland. arnaud.scherberich@usb.ch.
Miriam FilippiSoft Robotics Laboratory, ETH Zurich, Zurich, Switzerland. miriam.filippi@srl.ethz.ch.
University of Turin · ITETH Zurich · CHUniversity Hospital of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Iron deposits in cells and tissues can be detected by ex vivo histological examination through the Prussian blue (PB) staining. This practical, inexpensive, and highly sensitive technique involves the treatment of fixed tissue sections and cells with acid solutions of ferrocyanides that combine with ferric ion forming a bright blue pigment (i.e., ferric ferrocyanide). The staining can be applied to visualize iron oxide nanoparticles (IONPs), versatile magnetic nanosystems that are used in various biomedical applications and whose localization is usually required at a higher resolution than that enabled by in vivo tracking techniques.

Indexed as

Magnetite NanoparticlesNanoparticlesFerric CompoundsFerrocyanidesIronMagnetic Iron Oxide NanoparticlesMagnetic Resonance ImagingStaining and LabelingFerric Compoundsferric ferrocyanideFerrocyanidesIronMagnetite NanoparticlesFerric ironHistologyPerls’ stainingSuperparamagnetic iron oxide nanoparticles

Identifiers

PMID36152263
OpenAlexW4297174680

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.