Evidence map›Paper›PMID 36152237›Full record

ArticleMedical & biological engineering & computing2022

A deep learning approach to median nerve evaluation in ultrasound images of carpal tunnel inlet.

Mariachiara Di Cosmo, Maria Chiara Fiorentino, Francesca Pia Villani, Emanuele Frontoni, Gianluca Smerilli, Emilio Filippucci, Sara Moccia

Open access · hybridAbstract read
In one paragraph

Article in Medical & biological engineering & computing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
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  7. Carpal Tunnel Syndrome Diagnosis: A Narrative Review of Complementary Roles of Neuromuscular Ultrasound and Electrodiagnostic Studies.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Review
  8. A neuromuscular clinician's primer on machine learning.Journal of neuromuscular diseases · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Mariachiara Di CosmoDepartment of Information Engineering, Università Politecnica delle Marche, Via Brecce Bianche 12, 60131, Ancona, AN, Italy. m.dicosmo@pm.univpm.it.ORCID http://orcid.org/0000-0002-0269-4304
Maria Chiara FiorentinoDepartment of Information Engineering, Università Politecnica delle Marche, Via Brecce Bianche 12, 60131, Ancona, AN, Italy.
Francesca Pia VillaniDepartment of Humanities, Università di Macerata, Macerata, Italy.
Emanuele FrontoniDepartment of Political Sciences, Communication and International Relations, Università di Macerata, Macerata, Italy.
Gianluca SmerilliRheumatology Unit, Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, "Carlo Urbani" Hospital, Ancona, Italy.
Emilio FilippucciRheumatology Unit, Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, "Carlo Urbani" Hospital, Ancona, Italy.
Sara MocciaThe BioRobotics Institute, Department of Excellence in Robotics and AI, Scuola Superiore Sant'Anna, Pisa, Italy.
Marche Polytechnic University · ITUniversity of Macerata · ITScuola Superiore Sant'Anna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ultrasound (US) imaging is recognized as a useful support for Carpal Tunnel Syndrome (CTS) assessment through the evaluation of median nerve morphology. However, US is still far to be systematically adopted to evaluate this common entrapment neuropathy, due to US intrinsic challenges, such as its operator dependency and the lack of standard protocols. To support sonographers, the present study proposes a fully-automatic deep learning approach to median nerve segmentation from US images. We collected and annotated a dataset of 246 images acquired in clinical practice involving 103 rheumatic patients, regardless of anatomical variants (bifid nerve, closed vessels). We developed a Mask R-CNN with two additional transposed layers at segmentation head to accurately segment the median nerve directly on transverse US images. We calculated the cross-sectional area (CSA) of the predicted median nerve. Proposed model achieved good performances both in median nerve detection and segmentation: Precision (Prec), Recall (Rec), Mean Average Precision (mAP) and Dice Similarity Coefficient (DSC) values are 0.916 ± 0.245, 0.938 ± 0.233, 0.936 ± 0.235 and 0.868 ± 0.201, respectively. The CSA values measured on true positive predictions were comparable with the sonographer manual measurements with a mean absolute error (MAE) of 0.918 mm

Indexed as

Carpal Tunnel SyndromeDeep LearningBaysHumansMedian NerveUltrasonographyWristCarpal tunnel syndromeDeep learningMedian nerveSegmentationUltrasound imaging

Identifiers

PMID36152237
PMCPMC9537213
OpenAlexW4297175764

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.