Evidence map›Paper›PMID 36152210›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2023

Electrophysiology of Endocannabinoid Signaling.

Alessandra Musella, Diego Centonze

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Alessandra MusellaSynaptic Immunopathology Lab, IRCCS San Raffaele Roma, Rome, Italy.
Diego CentonzeDepartment of Systems Medicine, Tor Vergata University, Rome, Italy. centonze@uniroma2.it.
Istituti di Ricovero e Cura a Carattere Scientifico · ITUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electrophysiological technique is an efficient tool for investigating the synaptic regulatory effects mediated by the endocannabinoid system. Stimulation of presynaptic type 1 cannabinoid receptor (CB1) is the principal mode by which endocannabinoids suppress transmitter release in the central nervous system, but a non-retrograde manner of functioning and other receptors have also been described. Endocannabinoids are key modulators of both short- and long-term plasticity. Here, we discuss ex vivo electrophysiological approaches to examine synaptic signaling induced by cannabinoid and endocannabinoid molecules in the mammalian brain.

Indexed as

CannabinoidsEndocannabinoidsAnimalsCannabinoid Receptor ModulatorsMammalsReceptors, CannabinoidSignal TransductionSynaptic TransmissionCannabinoid Receptor ModulatorsCannabinoidsEndocannabinoidsReceptors, CannabinoidCannabinoidCB1 receptorDepolarization-induced suppression of excitation/inhibition (DSE/DSI)ElectrophysiologyLong-term plasticityMouseShort-term plasticity

Identifiers

PMID36152210
OpenAlexW4296931394

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.