Evidence map›Paper›PMID 36152203›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2023

DNA Methylation Analysis of Cnr1 Gene Promoter.

Claudio D'Addario, Mariangela Pucci

Registry-linked trialAbstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06595082 (Evaluation of the Consumption of Lupins in Brine on Metabolic Markers in Healthy Individuals), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06595082 nacompletednot on this mapstarted 2024, after this paper: background citation

Evaluation of the Consumption of Lupins in Brine on Metabolic Markers in Healthy Individuals

TypeinterventionalSponsorUniversity of TeramoRan2024 to 2024Enrolled60ConditionsLipid Disorder, Systemic Inflammatory ResponseArms4-week lupins in brine consumption, 4-week lupins in brine consumption and dietary suggestion
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Claudio D'AddarioFaculty of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, Teramo, Italy.
Mariangela PucciFaculty of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, Teramo, Italy. mpucci@unite.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA methylation pattern could be considered a biomarker to be exploited for the study and management of several human diseases. In this chapter, detailed protocols are provided for two experimental approaches used for quantitative methylation analysis of bisulfite converted DNA: methylation-specific PCR (MSP) and pyrosequencing.

Indexed as

DNADNA MethylationHumansPolymerase Chain ReactionPromoter Regions, GeneticReceptor, Cannabinoid, CB1Sequence Analysis, DNACNR1 protein, humanDNAReceptor, Cannabinoid, CB1DNA extractionDNA methylationMethylation-specific PCR (MSP)PyrosequencingType-1 cannabinoid receptor

Identifiers

PMID36152203

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.