Evidence map›Paper›PMID 36152187›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2023

Cellular Assay to Study β-Arrestin Recruitment by the Cannabinoid Receptors 1 and 2.

Jara Bouma, Marjolein Soethoudt, Noortje van Gils, Lizi Xia, Mario van der Stelt, Laura H Heitman

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. The Selective Serotonin 5‑HTACS pharmacology & translational science · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jara BoumaDivision of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands.
Marjolein SoethoudtDivision of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands.
Noortje van GilsDivision of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands.
Lizi XiaDivision of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands.
Mario van der SteltDepartment of Molecular Physiology, Leiden Institute of Chemistry, Leiden University, Leiden, the Netherlands.
Laura H HeitmanDivision of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands. l.h.heitman@lacdr.leidenuniv.nl.
Leiden University · NLCentre for Human Drug Research · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cannabinoid receptor 1 (CB

Indexed as

GTP-Binding ProteinsReceptors, G-Protein-Coupledbeta-Arrestin 1beta-Arrestinsbeta-GalactosidaseHumansLigandsReceptors, Cannabinoidbeta-Arrestin 1beta-Arrestinsbeta-GalactosidaseGTP-Binding ProteinsLigandsReceptors, CannabinoidReceptors, G-Protein-CoupledBiased signalingCannabinoid receptorsDesensitizationDiscoverX PathHunter®Functional selectivityGPCRsInternalizationReceptor signalingβ-arrestin

Identifiers

PMID36152187
OpenAlexW4296931358

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.