Evidence map›Paper›PMID 36152158›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2023

Analysis of Cholesterol from the Liver Using Gas Chromatography-Mass Spectrometry.

Meher A Saleem, Betsy Benitez, Charles Yaros, Gabrielle Yamar, Sanjoy K Bhattacharya

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Meher A SaleemBascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
Betsy BenitezBascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
Charles YarosBascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
Gabrielle YamarBascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
Sanjoy K BhattacharyaBascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA. sbhattacharya@med.miami.edu.
University of Miami · USGeorgetown University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cholesterol is an essential lipid molecule for several biological functions including the proper functioning of cell membranes, lipoproteins, and lipid rafts, as well as the synthesis of bile acids, vitamin D, and steroid hormones. Cholesterol can be extracted from liver tissue by multiple methods of lipid extraction. Subsequently, gas chromatography-mass spectrometry (GC-MS) can be used to obtain the highest level of sensitivity and selectivity in the analysis of cholesterol. This chapter describes two methods of lipid extraction for liver tissue, Bligh and Dyer and methyl tertiary butyl ether (MTBE), followed by an analysis with GC-MS.

Indexed as

CholesterolMethyl EthersBile Acids and SaltsGas Chromatography-Mass SpectrometryHormonesLiverVitamin DBile Acids and SaltsCholesterolHormonesMethyl EthersVitamin DBligh and DyerCholesterolGas chromatographyGCGC–MSLipid extractionLiverMass spectrometryMSMTBE

Identifiers

PMID36152158
OpenAlexW4297174687

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.