Evidence map›Paper›PMID 36151863›Full record

ArticleInternational journal of cancer2023

Circulating immune markers and risks of non-Hodgkin lymphoma subtypes: A pooled analysis.

Jongeun Rhee, Brenda M Birmann, Anneclaire J De Roos, Mara M Epstein, Otoniel Martinez-Maza, Elizabeth C Breen, Larry I Magpantay, Lynn I Levin, Kala Visvanathan, H Dean Hosgood and 13 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 12 institutions in 2 countries.

Jongeun RheeDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA.ORCID 0000-0003-1873-9359
Brenda M BirmannChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Anneclaire J De RoosDepartment of Environmental and Occupational Health, Dornsife School of Public Health, Drexel University, Philadelphia, Pennsylvania, USA.
Mara M EpsteinDepartment of Medicine and the Meyers Health Care Institute, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.ORCID 0000-0001-7906-4856
Otoniel Martinez-MazaDepartment of Microbiology, Immunology & Molecular Genetics, University of California, Los Angeles, Los Angeles, California, USA.
Elizabeth C BreenDepartment of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA.
Larry I MagpantayUCLA AIDS Institute, Los Angeles, California, USA.
Lynn I LevinStatistics and Epidemiology Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Kala VisvanathanJohns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, USA.
H Dean HosgoodDepartment of Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, New York, USA.
Thomas E RohanDepartment of Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, New York, USA.
Sylvia W SmollerDepartment of Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, New York, USA.
Bryan A BassigDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA.
Lihong QiDepartment of Public Health Sciences, University of California Davis, Davis, California, USA.
Xiao-Ou ShuDivision of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Woon-Puay KohHealthy Longevity Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Wei ZhengDivision of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.ORCID 0000-0003-1226-070X
Jian-Min YuanDivision of Cancer Control and Population Sciences, University of Pittsburgh Medical Center (UPMC) Hillman Cancer Center, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-4620-3108
Stephanie J WeinsteinDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA.
Demetrius AlbanesDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA.
Qing LanDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA.
Nathaniel RothmanDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA.ORCID 0000-0002-0866-9943
Mark P PurdueDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA.ORCID 0000-0003-1177-3108
National Cancer Institute · USAlbert Einstein College of Medicine · USUniversity of California, Los Angeles · USVanderbilt University · USAgency for Science, Technology and Research · SGBrigham and Women's Hospital · USDrexel University · USJohns Hopkins University · USUniversity of California, Davis · USUniversity of Massachusetts Chan Medical School · USUniversity of Pittsburgh · USWalter Reed Army Institute of Research · US

Funding

Staff InvestigatorsP30CA093373 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI Laura Marcu · 2002 to 2026
$84.9M
Statistical MethodsP01CA087969 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI TWOROGER, SHELLEY S · 2000 to 2019
$77.8M
Cancer Epidemiology Cohort in Male Health ProfessionalsU01CA167552 · NCI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Lorelei Mucci, Walter C. Willett · 2017 to 2026
$17.0M
Cancer Epidemiology Cohort in Male Health ProfessionalsUM1CA167552 · NCI · HARVARD SCHOOL OF PUBLIC HEALTH · PI WILLETT, WALTER C. · 2012 to 2016
$11.5M
BIOCHEMICAL MARKERS IN THE NURSES'HEALTH STUDY COHORTR01CA049449 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI HANKINSON, SUSAN E · 1989 to 2008
$11.3M
Multidisciplinary Studies of LymphomaZIACP010170 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI MORTON, LINDSAY · 2009 to 2025
$10.7M
Prospective studies of cancer etiology and prevention in Shanghai and SingaporeR01CA144034 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI YUAN, JIAN-MIN · 2010 to 2014
$7.0M
DIETARY FACTORS IN THE ETIOLOGY OF CANCER IN SHANGHAIR01CA043092 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI YUAN, JIAN-MIN · 1987 to 2006
$5.8M
THE SINGAPORE COHORT STUDY OF DIET AND CANCERR01CA080205 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI YUAN, JIAN-MIN · 1999 to 2009
$5.3M
Cancer epidemiology cohorts in Shanghai and Singapore UM1CA182876 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI YUAN, JIAN-MIN · 2014 to 2018
$4.3M
A prospective analysis of peripheral blood cytokines and non-Hodgkin lymphomaR01CA149445 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI BIRMANN, BRENDA M · 2011 to 2015
$3.0M
Exposure to Organochlorines, EBV, and the Risk of NHLR01CA098122 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI LADEN, FRANCINE · 2003 to 2006
$2.1M
Intramural NIH HHS Z99 CA999999NCI NIH HHS P01 CA087969NCI NIH HHS P30 CA093373NCI NIH HHS R01 CA043092NCI NIH HHS R01 CA049449NCI NIH HHS R01 CA080205NCI NIH HHS R01 CA098122NCI NIH HHS R01 CA144034NCI NIH HHS R01 CA149445NCI NIH HHS U01 CA167552NCI NIH HHS UM1 CA167552NCI NIH HHS UM1 CA182876
6 · The paper itself

Abstract

Although prediagnostic circulating concentrations of the immune activation markers soluble CD27 (sCD27), sCD30 and chemokine ligand-13 (CXCL13) have been associated with non-Hodgkin lymphoma (NHL) risk, studies have been limited by sample size in associations with NHL subtypes. We pooled data from eight nested case-control studies to investigate subtype-specific relationships for these analytes. Using polytomous regression, we calculated odds ratios (ORs) with 95% confidence intervals (CIs) relating study-specific analyte tertiles to selected subtypes vs controls (n = 3310): chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL; n = 623), diffuse large B cell lymphoma (DLBCL; n = 621), follicular lymphoma (FL; n = 398), marginal zone lymphoma (MZL; n = 138), mantle cell lymphoma (MCL; n = 82) and T cell lymphoma (TCL; n = 92). We observed associations with DLBCL for elevated sCD27 [OR for third vs first tertile (OR

Indexed as

Leukemia, Lymphocytic, Chronic, B-CellLymphoma, FollicularLymphoma, Large B-Cell, DiffuseLymphoma, Mantle-CellLymphoma, Non-HodgkinAdultBiomarkersCase-Control StudiesHumansBiomarkersCXCL13immune markersnon-Hodgkin lymphomasCD27sCD30

Identifiers

PMID36151863
PMCPMC9812887
OpenAlexW4297174468

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.