ArticleCritical care (London, England)2022
A novel capnogram analysis to guide ventilation during cardiopulmonary resuscitation: clinical and experimental observations.
Article in Critical care (London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 17 citations in OpenAlex.
- The impact of head and thorax elevation on respiratory mechanics during cardiopulmonary resuscitation: a multi-model study.Resuscitation plus · 2026Article
- Ventilation parameters during adult cardiopulmonary resuscitation: a systematic review.Resuscitation plus · 2026Article
- Bag-valve-endotracheal ventilation vs mechanical ventilation during cardiopulmonary resuscitation: a randomized experimental porcine study.Resuscitation plus · 2026Article
- Evaluation of ventilatory parameters reporting in large animal models of cardiac arrest: a scoping review.Resuscitation plus · 2026Article
- The Latest in Resuscitation Research: Highlights From the 2023 American Heart Association's Resuscitation Science Symposium.Journal of the American Heart Association · 2025Article
- A new physiological manikin to test and compare ventilation devices during cardiopulmonary resuscitation.Resuscitation plus · 2024Article
- Detecting Intrathoracic Airway Closure during Prehospital Cardiopulmonary Resuscitation Using Quasi-Static Pressure-Volume Curves: A Pilot Study.Journal of clinical medicine · 2024Article
Corrections and comments
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Authors and funding
18 authors at 11 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCardiopulmonary resuscitation (CPR) decreases lung volume below the functional residual capacity and can generate intrathoracic airway closure. Conversely, large insufflations can induce thoracic distension and jeopardize circulation. The capnogram (CO
objectivesTo test whether a specific capnogram may identify thoracic distension during CPR and to assess the impact of thoracic distension on gas exchange and hemodynamics.
methods(1) In out-of-hospital cardiac arrest patients, we identified on capnograms three patterns: intrathoracic airway closure, thoracic distension or regular pattern. An algorithm was designed to identify them automatically. (2) To link CO MEASUREMENTS AND MAIN
results(1) Clinical data: 202 capnograms were collected. Intrathoracic airway closure was present in 35%, thoracic distension in 22% and regular pattern in 43%. (2) Experiments: (i) Higher insufflated volumes reproduced thoracic distension CO
conclusionsDuring CPR, capnograms reflecting intrathoracic airway closure, thoracic distension or regular pattern can be identified. In the animal experiment, a thoracic distension pattern on the capnogram is associated with a negative impact of ventilation on blood pressure and cerebral perfusion during CPR, not predicted by tidal volume per se.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.