Evidence map›Paper›PMID 36151450›Full record

ArticleJournal of cardiovascular translational research2023

Transjugular Transcatheter Tricuspid Valve Implantation of LuX-Valve Bioprosthesis in a Preclinical Model.

Xiao-Ping Ning, Jing-Yi Cao, Meng-Xing Li, He Wang, Ning Li, Zhi-Gang Song, Zhi-Yun Xu, Lin Han, Guang-Wei Zhou, Xiao-Hong Liu and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of cardiovascular translational research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Xiao-Ping Ning *Department of Cardiovascular Surgery, Changhai Hospital affiliated to the Naval Medical University, Shanghai, 200433, China.ORCID 0000-0003-2382-9607
Jing-Yi Cao *Department of Cardiovascular Surgery, Changhai Hospital affiliated to the Naval Medical University, Shanghai, 200433, China.
Meng-Xing Li *Department of Thoracic Surgery, Changhai Hospital affiliated to the Naval Medical University, Shanghai, 200433, China.
He WangDepartment of Cardiovascular Surgery, Changhai Hospital affiliated to the Naval Medical University, Shanghai, 200433, China.
Ning LiDepartment of Cardiovascular Surgery, Changhai Hospital affiliated to the Naval Medical University, Shanghai, 200433, China.
Zhi-Gang SongDepartment of Cardiovascular Surgery, Changhai Hospital affiliated to the Naval Medical University, Shanghai, 200433, China.
Zhi-Yun XuDepartment of Cardiovascular Surgery, Changhai Hospital affiliated to the Naval Medical University, Shanghai, 200433, China.
Lin HanDepartment of Cardiovascular Surgery, Changhai Hospital affiliated to the Naval Medical University, Shanghai, 200433, China.
Guang-Wei ZhouDepartment of Cardiovascular Surgery, Changhai Hospital affiliated to the Naval Medical University, Shanghai, 200433, China.
Xiao-Hong LiuDepartment of Cardiovascular Surgery, Changhai Hospital affiliated to the Naval Medical University, Shanghai, 200433, China.
De-Jun GongDepartment of Cardiovascular Surgery, Changhai Hospital affiliated to the Naval Medical University, Shanghai, 200433, China.
Fan QiaoDepartment of Cardiovascular Surgery, Changhai Hospital affiliated to the Naval Medical University, Shanghai, 200433, China. qiaofan@smmu.edu.cn.
Fang-Lin LuDepartment of Cardiovascular Surgery, Changhai Hospital affiliated to the Naval Medical University, Shanghai, 200433, China. drlufanglin@yeah.net.
Second Military Medical University · CN

Funding

Pan Feng Project 2019YXK031the National Natural Science Foundation of China 82170376
6 · The paper itself

Abstract

The purpose of this preclinical study in a sheep model was to confirm the feasibility and safety of the LuX-Valve transjugular tricuspid valve (TV) replacement apparatus and to optimize the implantation procedure before beginning first-in-man study. The LuX-Valve was implanted in a sheep model (n = 8) via transjugular approach. Six of eight sheep underwent successful implantation procedure on beating heart. The first two sheep died during the prostheses deployment. In the remaining 6 sheep that survived, postoperative echocardiography results showed there was no paravalvular leakage (PVL) and central tricuspid regurgitation in 5 animals, whereas 1 animal had mild PVL. The mean transvalvular gradient was 1.1 ± 0.9 mm Hg at the 4-week follow-up. No right ventricular outflow tract (RVOT) obstruction, device malposition, pericardial effusion, coronary artery compression, or arrhythmias were observed. This technology may be a promising alternative for TR patients who are at high risk for open-heart surgery. Transjugular tricuspid valved-stent implantation. a Transjugular tricuspid valve replacement in a sheep model. b and c Valved stent. d, e, and f Schematic depiction of the implantation procedure.

Indexed as

BioprosthesisHeart Valve ProsthesisHeart Valve Prosthesis ImplantationAnimalsCardiac CatheterizationEchocardiographyProsthesis DesignSheepTreatment OutcomeTricuspid ValvePreclinical modelTranscatheter tricuspid valve replacementTricuspid regurgitationTricuspid valve

Identifiers

PMID36151450
OpenAlexW4297036566

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.