Evidence map›Paper›PMID 36151347›Full record

ArticleObesity surgery2022

Analysis of the Immunohistochemical Expression of Ghrelin in the Gastric Mucosa and Correlation with Weight Loss After Sleeve Gastrectomy.

Reynaldo Martins E Quinino, André Luis Costa Barbosa, Maíra de Araújo Barros Xavier, Romero de Lima França, Mirella Patrícia Cruz de Freitas, Alberto Goldenberg

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Article in Obesity surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Reynaldo Martins E QuininoDepartment of Integrated Medicine at the Universidade Federal Do Rio Grande Do Norte, Rua Raimundo Chaves 1652, Casa i 13 Natal, Candelária, RN, 59064-390, Brazil. reynaldoquinino@yahoo.com.br.ORCID 0000-0002-4284-2543
André Luis Costa BarbosaSurgery Service for Obesity and Associated Diseases at Hospital, Universitário Onofre Lopes, Av. Nilo Peçanha, 620 Natal, Petrópolis, RN, 59012-300, Brazil.
Maíra de Araújo Barros XavierHospital Universitário Onofre Lopes, Av. Nilo Peçanha, 620 Natal, Petrópolis, RN, 59012-300, Brazil.
Romero de Lima FrançaHospital Universitário Onofre Lopes, Av. Nilo Peçanha, 620 Natal, Petrópolis, RN, 59012-300, Brazil.
Mirella Patrícia Cruz de FreitasHospital Universitário Onofre Lopes, Av. Nilo Peçanha, 620 Natal, Petrópolis, RN, 59012-300, Brazil.
Alberto GoldenbergDepartment of Surgery, Escola Paulista de Medicina, Universidade Federal de São Paulo, R. Napoleão de Barros, 715 Vila Clementino, São Paulo, SP, 04024-002, Brazil.
Hospital Universitário Onofre Lopes · BRUniversidade Federal de São Paulo · BRUniversidade Federal do Rio Grande do Norte · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSleeve gastrectomy is one of the main techniques used to treat severe obesity. The study of the immunohistochemical expression of ghrelin in the gastric mucosa has already been related to weight loss and can be a promising method to predict the surgical outcome. PURPOSE: To analyze the immunohistochemical expression of ghrelin in the gastric mucosa and its correlation with weight loss, comorbidities, and inflammatory changes after sleeve gastrectomy.

methodsThirty-five patients submitted to sleeve gastrectomy were evaluated, 29 of whom were female (82.9%), with a mean age of 35.2 years and an average body mass index of 38.1 kg/m

resultsThe average total weight loss (TWL%) was 17.7, 26.4, and 32.1%, respectively, at 3, 6, and 12 months. A negative correlation was found between the immunohistochemical expression of ghrelin in the endoscopic biopsy of the fundus and weight loss at 3 (s =  - 0.536; p = 0.001) and 6 months (s =  - 0.339; p = 0.047).

conclusionThe immunohistochemical expression of ghrelin in the mucosa of the gastric fundus was negatively correlated with early weight loss after sleeve gastrectomy.

Indexed as

Gastric BypassLaparoscopyObesity, MorbidAdultFemaleGastrectomyGastric MucosaGhrelinHumansImmunohistochemistryMaleWeight LossGhrelinBariatric SurgeryGhrelinImmunochemistry

Identifiers

PMID36151347
OpenAlexW4297017674

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.