Evidence map›Paper›PMID 36151340›Full record

ArticlePediatric surgery international2022

Sexual function and fertility of adult males with anorectal malformations or Hirschsprung disease.

Marina L Reppucci, Lea A Wehrli, Duncan Wilcox, Jill Ketzer, Alberto Pena, Luis de la Torre, Andrea Bischoff, Dan Wood

Abstract read
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In one paragraph

Article in Pediatric surgery international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Evaluating the Empowerment Potential of an International Sexual Support Website for Patients with Anorectal Malformations and Hirschsprung Disease, their Parents and Healthcare Providers.European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie · 2025
    Article
  2. Article
  3. Anorectal Malformations and Late-Term Problems.Turkish archives of pediatrics · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Marina L ReppucciInternational Center for Colorectal and Urogenital Care, Children's Hospital Colorado, Aurora, CO, USA.
Lea A WehrliInternational Center for Colorectal and Urogenital Care, Children's Hospital Colorado, Aurora, CO, USA.
Duncan WilcoxInternational Center for Colorectal and Urogenital Care, Children's Hospital Colorado, Aurora, CO, USA.
Jill KetzerInternational Center for Colorectal and Urogenital Care, Children's Hospital Colorado, Aurora, CO, USA.
Alberto PenaInternational Center for Colorectal and Urogenital Care, Children's Hospital Colorado, Aurora, CO, USA.
Luis de la TorreInternational Center for Colorectal and Urogenital Care, Children's Hospital Colorado, Aurora, CO, USA.
Andrea BischoffInternational Center for Colorectal and Urogenital Care, Children's Hospital Colorado, Aurora, CO, USA.
Dan WoodInternational Center for Colorectal and Urogenital Care, Children's Hospital Colorado, Aurora, CO, USA. dan.wood@childrenscolorado.org.
Children's Hospital Colorado · USUniversity of Colorado Denver · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe long-term impact of anorectal malformations (ARM) and Hirschsprung disease (HD) on sexual function is well recognized but understudied. This study evaluated self-reported sexual and fertility outcomes in adult males with ARM and HD.

methodsThis was an IRB approved, prospective study of males in the Adult Colorectal Research Registry who completed surveys between October 2019 and March 2022. Electronic surveys were administered after consenting to being contacted for research. Patients completed the International Index of Erectile Function (IIEF) questionnaire and provided information on fertility outcomes.

resultsSixty-five patients completed outcome questionnaires: 11 (16.9%) had HD and 54 (83.1%) had an ARM. Nineteen patients reported some degree of erectile dysfunction per IIEF criteria, a greater proportion of whom have ARM (p = 0.046). Twenty (30.7%) have reported having children; there were no differences in rates between HD and ARM patients. Most patients had not attempted to conceive, but eight patients, all of whom have ARM, have pursued fertility investigation or treatments.

conclusionMore patients with ARM reported some degree of erectile dysfunction compared to those with HD. Additionally, some have required fertility treatments. Further investigation is warranted to ensure true low rates of sexual and fertility dysfunction in patients with HD.

Indexed as

Anorectal MalformationsHirschsprung DiseaseAdultErectile DysfunctionFertilityHumansMaleProspective StudiesSurveys and QuestionnairesAnorectal malformationErectile functionFertilityHirschsprung diseaseSexual function

Identifiers

PMID36151340
OpenAlexW4296840402

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.