Evidence map›Paper›PMID 36150435›Full record

ArticleEnvironmental research2022

Residential proximity to agricultural pesticide use and risk-taking behaviors in young adults from the CHAMACOS study.

Robert B Gunier, Julianna Deardorff, Stephen Rauch, Patrick T Bradshaw, Katherine Kogut, Sharon Sagiv, Carly Hyland, Ana Maria Mora, Brenda Eskenazi

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environmental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Robert B GunierSchool of Public Health, University of California, Berkeley, CA, USA. Electronic address: gunier@berkeley.edu.
Julianna DeardorffSchool of Public Health, University of California, Berkeley, CA, USA.
Stephen RauchSchool of Public Health, University of California, Berkeley, CA, USA.
Patrick T BradshawSchool of Public Health, University of California, Berkeley, CA, USA.
Katherine KogutSchool of Public Health, University of California, Berkeley, CA, USA.
Sharon SagivSchool of Public Health, University of California, Berkeley, CA, USA.
Carly HylandSchool of Public Health and Population Science, Boise State University, Boise, ID, USA.
Ana Maria MoraSchool of Public Health, University of California, Berkeley, CA, USA.
Brenda EskenaziSchool of Public Health, University of California, Berkeley, CA, USA.
University of California, Berkeley · USBoise State University · US

Funding

Project C: Epigenetic Effects of DDT/E and PBDEs on PubertyP01ES009605 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI ESKENAZI, BRENDA · 1999 to 2015
$11.2M
Effect of early life exposure to social adversity and pesticides on risk-taking behavior of 16-18 year olds: the CHAMACOS studyR01ES026994 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI ESKENAZI, BRENDA · 2016 to 2020
$3.9M
DDT & PBDE exposure, puberty onset and neurodevelopment in Mexican-American girlsR01ES017054 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI ESKENAZI, BRENDA · 2009 to 2013
$3.2M
Maintaining and Expanding the CHAMACOS Epidemiology Cohort Infrastructure for Future GenerationsR24ES028529 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Robert Gunier · 2017 to 2026
$2.0M
Long-term sequelae of early life pesticide exposure in the CHAMACOS birth cohortUH3ES030631 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI ESKENAZI, BRENDA · 2019 to 2020
$1000k
NIEHS NIH HHS P01 ES009605NIEHS NIH HHS R01 ES017054NIEHS NIH HHS R01 ES026994NIEHS NIH HHS R24 ES028529NIEHS NIH HHS UH3 ES030631
6 · The paper itself

Abstract

backgroundPrenatal pesticide exposure has been associated with poorer neurodevelopment during childhood, which could lead to greater risk-taking behaviors and delinquency in adolescence. This association may be augmented by adversity exposure.

objectivesEvaluate the relationship between prenatal pesticide exposure and risk-taking behavior in young adults at 18-years of age. Assess whether adversity exposure modifies these associations.

methodsParticipants included mother-child dyads (n = 467) enrolled in the Center for the Health Assessment of Mothers and Children Of Salinas (CHAMACOS) study, a longitudinal birth cohort set in the agricultural Salinas Valley of California. We estimated agricultural pesticide use within one km of maternal residences during pregnancy using a geographic information system, residential addresses, and California's Pesticide Use Reporting data. We used Bayesian hierarchical regression to evaluate associations of prenatal exposure to a mixture of 11 neurotoxic pesticides with self-reported police encounters, risk-taking behaviors, and unique types and frequency of delinquent acts. We also evaluated effect modification of these relationships by adversity exposure.

resultsWe observed generally null associations of neurotoxic pesticide use with risk-taking behaviors. Prenatal residential proximity to chlorpyrifos use was associated with higher risk of a police encounter, a delinquent act, and higher incidence of both unique types of acts committed and total frequency of delinquent acts. Prenatal residential proximity to dimethoate use was associated with a higher incidence of police encounters and methomyl with a higher risk of committing a delinquent act. There were no consistent differences when stratified by the number of adverse childhood experiences.

conclusionsWe observed mostly null associations between prenatal residential proximity to agricultural pesticide use and risk-taking behaviors at age 18, with little evidence of effect modification by childhood adversity. There were suggestive associations for chlorpyrifos use with having any police encounter and with all measures of delinquent acts that warrant confirmation in other studies.

Indexed as

ChlorpyrifosPesticidesPrenatal Exposure Delayed EffectsAdolescentBayes TheoremCaliforniaDimethoateEnvironmental ExposureFemaleHumansMethomylPregnancyRisk-TakingYoung AdultChlorpyrifosDimethoateMethomylPesticidesBehaviorChildhood adversityDelinquencyGeographic information system (GIS) modelsPesticidesRisk-takingYoung adults

Identifiers

PMID36150435
PMCPMC10535360
OpenAlexW4296391815

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.