ArticleScience immunology2022
A Stk4-Foxp3-NF-κB p65 transcriptional complex promotes T
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Article in Science immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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0cells of the map it votes in
16citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
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Who cites it
16 citing papers in PubMed, 25 citations in OpenAlex.
- Single-cell transcriptomics identifies regulatory T cell heterogeneity in gestational diabetes mellitus.Communications medicine · 2026Article
- Review
- Serine/Threonine Kinase 4 Deficiency Caused by a Potential Novel c.248del, p.Pro83Leufs∗3 Mutation: A Case Report.Case reports in immunology · 2026Article
- Kinase signaling in the control of regulatory T cell function: molecular mechanisms and therapeutic implications.Frontiers in immunology · 2026Review
- Notch3 destabilizes regulatory T cells to drive autoimmune neuroinflammation in multiple sclerosis.Immunity · 2025Article
- Serine/threonine kinase 33 mediates thrombin-induced interleukin-8 release from human lung epithelial cells in severe asthma.Respiratory research · 2025Article
- Long non-coding RNA ANRIL/p65 negative feedback loop protects intestinal barrier function in inflammatory bowel disease.Non-coding RNA research · 2025Article
- The NF-κB signaling network in the life of T cells.Frontiers in immunology · 2025Review
- Mesenchymal Stem Cell-Derived Exosomes Inhibit Stim1-Orai1 Signaling and Calcium Overload-Induced Mitochondrial Damage of Follicular Helper T Cells in Lupus.Biomaterials research · 2025Article
- Dynamic Foxp3-chromatin interaction controls tunable Treg cell function.The Journal of experimental medicine · 2024Article
- Functional CRISPR screens in T cells reveal new opportunities for cancer immunotherapies.Molecular cancer · 2024Review
- NF-κB in biology and targeted therapy: new insights and translational implications.Signal transduction and targeted therapy · 2024Review
- Elusive modes of Foxp3 activity in versatile regulatory T cells.Frontiers in immunology · 2024Review
- Non-canonical NFKB signaling endows suppressive function through FOXP3-dependent regulatory T cell program.Heliyon · 2023Article
- Severe allergic dysregulation due to a gain of function mutation in the transcription factor STAT6.The Journal of allergy and clinical immunology · 2023Article
- [Changes in percentage of GATA3Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2023Article
Corrections and comments
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Authors and funding
20 authors at 7 institutions in 3 countries.
Ye CuiDivision of Immunology, Boston Children's Hospital, Boston, MA, USA.ORCID 0000-0001-9428-1429
Mehdi BenamarDivision of Immunology, Boston Children's Hospital, Boston, MA, USA.ORCID 0000-0003-1532-8642
Klaus Schmitz-AbeDivision of Immunology, Boston Children's Hospital, Boston, MA, USA.ORCID 0000-0002-7242-8861
Varsha Poondi-KrishnanInstitute of Genetics and Biophysics "Adriano Buzzati-Traverso", Consiglio Nazionale delle Ricerche, Naples, Italy.ORCID 0000-0002-4002-0511
Qian ChenDivision of Immunology, Boston Children's Hospital, Boston, MA, USA.ORCID 0000-0002-7771-2802
Bat-Erdene JugderDivision of Immunology, Boston Children's Hospital, Boston, MA, USA.ORCID 0000-0002-8893-1170
Benoit FatouDepartment of Pathology, Boston Children's Hospital-Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-0317-0243
Jason FongDivision of Immunology, Boston Children's Hospital, Boston, MA, USA.ORCID 0000-0001-6164-6110
Yuelin ZhongDivision of Immunology, Boston Children's Hospital, Boston, MA, USA.ORCID 0000-0002-7414-3755
Stuti MehtaDana Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA.ORCID 0000-0002-6810-6771
Altantsetseg BuyanbatDana Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA.
Beray Selver EkliogluDepartment of Pediatrics, Meram Medical Faculty, Necmettin Erbakan University, Konya, Turkey.
Esra KarabiberMarmara University, Pendik Training And Research Hospital, Department of Chest Disease, Division of Adult Immunology and Allergy, Istanbul, Turkey.
Safa BarisMarmara University, Faculty of Medicine, Division of Pediatric Allergy and Immunology, Istanbul, Turkey.ORCID 0000-0002-4730-9422
Ayca KiykimDivision of Pediatric Allergy and Immunology, Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.ORCID 0000-0001-5821-3963
Sevgi KelesDepartment of Pediatrics, Meram Medical Faculty, Necmettin Erbakan University, Konya, Turkey.
Emmanuel Stephen-VictorDivision of Immunology, Boston Children's Hospital, Boston, MA, USA.ORCID 0000-0001-5049-7017
Claudia AngeliniIstituto per le Applicazioni del Calcolo "M. Picone", Consiglio Nazionale delle Ricerche, Naples, Italy.ORCID 0000-0001-8350-8464
Louis-Marie CharbonnierDivision of Immunology, Boston Children's Hospital, Boston, MA, USA.ORCID 0000-0002-4594-7893
Talal A ChatilaDivision of Immunology, Boston Children's Hospital, Boston, MA, USA.ORCID 0000-0001-7439-2762
Boston Children's Hospital · USDana-Farber/Boston Children's Cancer and Blood Disorders Center · USMarmara University · TRNecmettin Erbakan University · TRInstitute of Genetics and Biophysics · ITIstanbul University-Cerrahpaşa · TRIstituto per le Applicazioni del Calcolo Mauro Picone · IT
Funding
Mechanisms of Disease Pathogenesis in Regulatory T cell DeficiencyR01AI085090 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CHATILA, TALAL AMINE, WILLIAMS, CALVIN B · 2010 to 2020
$3.9MReprogramming of Regulatory T cells to Promote Immune ToleranceR01AI153174 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI CHARBONNIER, LOUIS-MARIE · 2020 to 2024
$2.2MMechanisms of Combined Immunodeficiency due to DOCK8 DeficiencyR01AI128976 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI CHATILA, TALAL AMINE · 2018 to 2021
$1.4MNIAID NIH HHS R01 AI085090NIAID NIH HHS R01 AI128976NIAID NIH HHS R01 AI153174
Abstract
The molecular programs involved in regulatory T (T
Indexed as
Forkhead Transcription FactorsNF-kappa BProtein Serine-Threonine KinasesT-Lymphocytes, RegulatoryAnimalsHippo KinasesHomeostasisMiceReceptors, Antigen, T-CellSerineTranscription Factor RelAForkhead Transcription FactorsFoxp3 protein, mouseHippo KinasesNF-kappa BProtein Serine-Threonine KinasesReceptors, Antigen, T-CellRela protein, mouseSerineStk4 protein, mouseTranscription Factor RelA
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.