Evidence map›Paper›PMID 36149904›Full record

ArticlePloS one2022

Voluntary medical male circumcision in selected provinces in South Africa: Outcomes from a programmatic setting.

Khumbulani Moyo, Nelson Igaba, Constance Wose Kinge, Charles Chasela, Motshana Phohole, Skye Grove, Caroline Makura, Latisani Mudau, Dirk Taljaard, Dino Rech and 4 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. A comparative analysis of voluntary medical male circumcision before and during the COVID-19 pandemic in Gauteng province, South Africa.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Khumbulani MoyoRight to Care, Johannesburg, South Africa.
Nelson IgabaRight to Care, Johannesburg, South Africa.
Constance Wose KingeRight to Care, Johannesburg, South Africa.
Charles ChaselaRight to Care, Johannesburg, South Africa.ORCID 0000-0001-8362-5986
Motshana PhoholeRight to Care, Johannesburg, South Africa.
Skye GroveRight to Care, Johannesburg, South Africa.ORCID 0000-0002-3792-1685
Caroline MakuraRight to Care, Johannesburg, South Africa.
Latisani MudauRight to Care, Johannesburg, South Africa.
Dirk TaljaardCentre for HIV and AIDS Prevention Studies (CHAPS), Johannesburg, South Africa.
Dino RechCentre for HIV and AIDS Prevention Studies (CHAPS), Johannesburg, South Africa.
Arthi RamkissoonMaternal Adolescent and Child Health (MatCH), Durban, South Africa.
Catherine SearleMaternal Adolescent and Child Health (MatCH), Durban, South Africa.
Pappie MajubaRight to Care, Johannesburg, South Africa.
Ian SanneRight to Care, Johannesburg, South Africa.
Right to Care · ZAUniversity of the Witwatersrand · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionVoluntary medical male circumcision (VMMC) remains an effective biomedical intervention for HIV prevention in high HIV prevalence countries. In South Africa, United States Agency for International Development VMMC partners provide technical assistance to the Department of Health, at national and provincial levels in support of the establishment of VMMC sites as well as in providing direct VMMC services at site level since April 2012. We describe the outcomes of the Right to Care (RTC) VMMC program implemented in South Africa from 2012 to 2017.

methodsThis retrospective study was undertaken at RTC supported facilities across six provinces. Young males aged ≥10 years who presented at these facilities from 1 July 2012 to 31 September 2017 were included. Outcomes were VMMC uptake, HIV testing uptake and rate of adverse events (AEs). Using a de-identified observational database of these clients, summary statistics of the demographic characteristics and outcomes were calculated.

resultsThere were a total 1,001,226 attendees of which 998,213 (99.7%) were offered VMMC and had a median age of 15 years (IQR = 12-23 years). Of those offered VMMC, 99.6% (994,293) consented, 96.7% (965,370) were circumcised and the majority (46.3%) were from Gauteng province. HIV testing uptake was 71% with a refusal rate of 15%. Of the newly diagnosed HIV positives, 64% (6,371 / 9,972) referrals were made. The rate of AEs, defined as bleeding, infection, and insufficient skin removal) declined from 3.26% in 2012 to 1.17% in 2017. There was a reduction in infection-related AEs from 2,448 of the 2,602 adverse events (94.08%) in 2012 to 129 of the 2,069 adverse events (6.23%) in 2017.

conclusionThere was a high VMMC uptake with a decline in AEs over time. Adolescent men contributed the most to the circumcised population, an indication that the young population accesses medical circumcision more. VMMC programs need to implement innovative demand creation strategies to encourage older males (20-34 years) at higher risk of HIV acquisition to get circumcised for immediate impact in reduction of HIV incidence. HIV prevalence in the total population increased with increasing age, notably in clients above 25 years.

Indexed as

Circumcision, MaleHIV InfectionsAdolescentAdultChildHumansMaleRetrospective StudiesSouth AfricaVoluntary ProgramsYoung Adult

Identifiers

PMID36149904
PMCPMC9506619
OpenAlexW4296794359

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.