Evidence map›Paper›PMID 36149891›Full record

ArticlePLoS biology2022

Pathogen evolution during vaccination campaigns.

Troy Day, David A Kennedy, Andrew F Read, Sylvain Gandon

Abstract read
In one paragraph

Article in PLoS biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. The speed of vaccination rollout and the risk of pathogen adaptation.Journal of the Royal Society, Interface · 2025
    Article
  7. Article
  8. Article
  9. Decoding the cross-immune pressure: Dengue's role in SARS-CoV-2 evolution.Computational and structural biotechnology journal · 2025
    Article
  10. Review
  11. Mathematical modelling for pandemic preparedness in Canada: Learning from COVID-19.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2024
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Troy DayDepartment of Mathematics and Statistics, Department of Biology, Queen's University, Kingston, Ontario, Canada.ORCID 0000-0002-1052-6140
David A KennedyDepartment of Biology, Pennsylvania State University, University Park, Pennsylvania, United States of America.ORCID 0000-0003-0820-115X
Andrew F ReadDepartment of Biology, Pennsylvania State University, University Park, Pennsylvania, United States of America.
Sylvain GandonCEFE, CNRS, Univ Montpellier, EPHE, IRD, Montpellier, France.ORCID 0000-0003-2624-7856

Funding

US-UK Collab: The consequences of transmissible vaccines on disease ecology and pathogen evolution: Marek's disease virus as a case studyR01GM140459 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI KENNEDY, DAVID · 2020 to 2024
$1.7M
Vaccines as drivers of disease emergence: transmission ecology and virulence evolR01GM105244 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI READ, ANDREW F. · 2012 to 2016
$1.2M
NIGMS NIH HHS R01 GM105244NIGMS NIH HHS R01 GM140459
6 · The paper itself

Abstract

Following the initiation of the unprecedented global vaccination campaign against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), attention has now turned to the potential impact of this large-scale intervention on the evolution of the virus. In this Essay, we summarize what is currently known about pathogen evolution in the context of immune priming (including vaccination) from research on other pathogen species, with an eye towards the future evolution of SARS-CoV-2.

Indexed as

COVID-19SARS-CoV-2HumansImmunization ProgramsVaccination

Identifiers

PMID36149891
PMCPMC9553060

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.