Evidence map›Paper›PMID 36149770›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2022

Role of BH

Lyndsey E DuBose, Cemal Ozemek, Tyler Wick, Vanessa Richardson, Kerry L Hildreth, Kerrie L Moreau

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Effects of dietary soy content on cerebral artery function and behavior in ovariectomized female mice.American journal of physiology. Heart and circulatory physiology · 2024
    Article
  7. Sex as a biological variable for cardiovascular physiology.American journal of physiology. Heart and circulatory physiology · 2024
    Review
  8. Impact of aging on vascular ion channels: perspectives and knowledge gaps across major organ systems.American journal of physiology. Heart and circulatory physiology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Lyndsey E DuBoseDivision of Geriatric Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado.ORCID 0000-0002-3566-4531
Cemal OzemekDivision of Geriatric Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
Tyler WickDepartment of Biostatistics and Informatics, University of Colorado Anschutz Medical Campus, Aurora, Colorado.ORCID 0000-0003-1586-2896
Vanessa RichardsonDepartment of Biostatistics and Informatics, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
Kerry L HildrethDivision of Geriatric Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado.ORCID 0000-0001-7463-7811
Kerrie L MoreauDivision of Geriatric Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado.ORCID 0000-0001-9298-047X
University of Colorado Anschutz Medical Campus · USGeriatric Research Education and Clinical Center · USUniversity of Illinois Chicago · US

Funding

NIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1M
PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI BRYAN C BERGMAN · 1995 to 2026
$32.6M
University of Colorado Aging Training GrantT32AG000279 · NIA · UNIVERSITY OF COLORADO DENVER · PI Kerrie Moreau · 2001 to 2026
$10.1M
Biological Mechanisms of Arterial Stiffening With Age and Estrogen DeficiencyR01AG027678 · NIA · UNIVERSITY OF COLORADO DENVER · PI MOREAU, KERRIE · 2006 to 2010
$1.5M
Biological Mechanisms of Vascular Dysfunction with Age and Estrogen DeficiencyR56HL114073 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI MOREAU, KERRIE · 2013 to 2013
$651k
Ovarian Hormone Regulation of Central and Cerebrovascular HemodynamicsF32AG071273 · NIA · UNIVERSITY OF COLORADO DENVER · PI DUBOSE, LYNDSEY · 2021 to 2022
$122k
NCATS NIH HHS UL1 TR002535NHLBI NIH HHS R56 HL114073NIA NIH HHS F32 AG071273NIA NIH HHS R01 AG027678NIA NIH HHS T32 AG000279NIDDK NIH HHS P30 DK048520
6 · The paper itself

Abstract

Endothelial function (brachial artery flow-mediated dilation [FMD]) is reduced in estrogen-deficient postmenopausal women, mediated, in part, by reduced nitric oxide (NO) bioavailability, secondary to tetrahydrobiopterin (BH

Indexed as

Nitric Oxide Synthase Type IIIVascular DiseasesBiopterinsEndothelium, VascularEstrogensFemaleHumansMenopauseNitric OxideOxidative StressPeroxynitrous AcidBiopterinsEstrogensNitric OxideNitric Oxide Synthase Type IIIPeroxynitrous Acidagingendothelial functionmenopausenitric oxide bioavailability

Identifiers

PMID36149770
PMCPMC9621706
OpenAlexW4296807209

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.