Evidence map›Paper›PMID 36149725›Full record

ArticleCancer biotherapy & radiopharmaceuticals2023

Radiochemical Quality Control Methods for Radium-223 and Thorium-227 Radiotherapies.

Abbie Hasson, Wen Jiang, Nadia Benabdallah, Peng Lu, Mark S Longtine, Bradley J Beattie, Lucy Summer, Hanwen Zhang, Richard L Wahl, Diane S Abou and 1 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer biotherapy & radiopharmaceuticals, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07356466 (Clinical Efficacy of Pucotenlimab Combined With Lenvatinib and SOX Versus SOX Alone in Patients With HER2-Negative Advanced Gastric or Gastroesophageal Junction Adenocarcinoma), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07356466 early_phase1enrolling by invitationnot on this mapstarted 2025, after this paper: background citation

Clinical Efficacy of Pucotenlimab Combined With Lenvatinib and SOX Versus SOX Alone in Patients With HER2-Negative Advanced Gastric or Gastroesophageal Junction Adenocarcinoma: A Single-Center Randomized Controlled Trial

TypeinterventionalSponsorFujian Medical UniversityRan2025 to 2030Enrolled100ConditionsGastric (Stomach) CancerArmsPucotenlimab Combined with Lenvatinib, Oxaliplatin plus S-1 regimen
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Beyond Average: α-Particle Distribution and Dose Heterogeneity in Bone Metastatic Prostate Cancer.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Article
  2. Evaluation of Candidate Theranostics forJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Abbie HassonDepartment of Biomedical Engineering, Washington University, St. Louis, Missouri, USA.
Wen JiangDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, USA.
Nadia BenabdallahDepartment of Radiology, Program in Quantitative Molecular Therapeutics, Washington University School of Medicine, St. Louis, Missouri, USA.
Peng LuDepartment of Biomedical Engineering, Washington University, St. Louis, Missouri, USA.
Mark S LongtineDepartment of Radiology, Program in Quantitative Molecular Therapeutics, Washington University School of Medicine, St. Louis, Missouri, USA.
Bradley J BeattieDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.ORCID 0000-0001-9891-8271
Lucy SummerDepartment of Radiology, Program in Quantitative Molecular Therapeutics, Washington University School of Medicine, St. Louis, Missouri, USA.ORCID 0000-0002-7735-8612
Hanwen ZhangDepartment of Radiology, Program in Quantitative Molecular Therapeutics, Washington University School of Medicine, St. Louis, Missouri, USA.
Richard L WahlDepartment of Radiology, Program in Quantitative Molecular Therapeutics, Washington University School of Medicine, St. Louis, Missouri, USA.
Diane S AbouDepartment of Radiology, Program in Quantitative Molecular Therapeutics, Washington University School of Medicine, St. Louis, Missouri, USA.
Daniel L J ThorekDepartment of Biomedical Engineering, Washington University, St. Louis, Missouri, USA.ORCID 0000-0003-2437-1239

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
The Radium-223 Combination Therapy Space; Improving Response and Clarifying ToxicitiesR01CA240711 · NCI · WASHINGTON UNIVERSITY · PI MICHALSKI, JEFF M., THOREK, DANIEL LYNDON JAFFE · 2020 to 2024
$2.2M
Opening the Therapeutic Window for PSMA-Targeted Molecular RadiotherapyR01CA229893 · NCI · WASHINGTON UNIVERSITY · PI THOREK, DANIEL LYNDON JAFFE · 2019 to 2024
$1.9M
NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA229893NCI NIH HHS R01 CA240711
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

RadiopharmaceuticalsRadiumHumansQuality ControlRadioisotopesThoriumRadioisotopesRadiopharmaceuticalsRadiumRadium-223ThoriumThorium-227quality controlradio-thin layer chromatographyα particle therapyγ counter

Identifiers

PMID36149725
PMCPMC9940811

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.