Evidence map›Paper›PMID 36149614›Full record

ArticleJournal of assisted reproduction and genetics2022

Comment on the recent PGDIS Position Statement on the Transfer of Mosaic Embryos 2021.

Maximilian Murtinger, Maximilian Schuff, Barbara Wirleitner, Susanna Miglar, Dietmar Spitzer

Abstract readEditorial
In one paragraph

Article in Journal of assisted reproduction and genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maximilian MurtingerNext Fertility IVF Prof. Zech - Bregenz, Bregenz, Austria. maximilian.murtinger@ivf.at.ORCID http://orcid.org/0000-0001-9679-9264
Maximilian SchuffNext Fertility IVF Prof. Zech - Bregenz, Bregenz, Austria.
Barbara WirleitnerNext Fertility IVF Prof. Zech - Bregenz, Bregenz, Austria.
Susanna MiglarNext Fertility IVF Prof. Zech - Salzburg, Salzburg, Austria.
Dietmar SpitzerNext Fertility IVF Prof. Zech - Salzburg, Salzburg, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The worldwide demand of preimplantation genetic testing for aneuploidy (PGT-A) is still growing. However, chromosomal mosaic results greatly challenge the clinical practice. The recently published PGDIS Position Statement on the Transfer of Mosaic Embryos is the third PGDIS position statement on how to deal with embryos diagnosed as chromosomal mosaics (CM) and, one of many attempts of different societies and working groups to provide a guideline for clinicians, laboratories, clinics, and genetic counselors. But still, as in previous statements, many issues remained unresolved. Moreover, from our point of view, the question how to deal with embryos diagnosed as CM, consisting of two or more karyological cell lines cannot be separated from all the other aspects of PGT-A including its accuracy. The paucity of clearcut indications for PGT-A and evidence of benefit as well as an overall cost-benefit assessment is given below.

Indexed as

Preimplantation DiagnosisAneuploidyChromosomesConsensus Statements as TopicFemaleGenetic TestingHigh-Throughput Nucleotide SequencingHumansPregnancyAneuploidyEvidence-based medicinePGT-ATrophectoderm biopsy

Identifiers

PMID36149614
PMCPMC9723048

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.