Evidence map›Paper›PMID 36149594›Full record

ReviewCurrent osteoporosis reports2022

Skeletal Muscle Complications in Chronic Kidney Disease.

Ashley D Troutman, Eliott Arroyo, Kenneth Lim, Ranjani N Moorthi, Keith G Avin

Open access · greenAbstract readReview
In one paragraph

Review in Current osteoporosis reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ashley D TroutmanDepartment of Physical Therapy, School of Health and Human Sciences, Indiana University Purdue University, CF-326, 1140 W. Michigan St., Indianapolis, IN, 46202, USA.
Eliott ArroyoDivision of Nephrology & Hypertension, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
Kenneth LimDivision of Nephrology & Hypertension, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
Ranjani N MoorthiDivision of Nephrology & Hypertension, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
Keith G AvinDepartment of Physical Therapy, School of Health and Human Sciences, Indiana University Purdue University, CF-326, 1140 W. Michigan St., Indianapolis, IN, 46202, USA. keigavin@iu.edu.ORCID 0000-0001-9426-7862
Indiana University School of MedicineIndiana University – Purdue University Indianapolis · US

Funding

Quality Assurance and Quality Control Project Management: Improving Submissions and Study Conduct in the Human Subjects Research Prior Approval ProcessUL1TR002529 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI MOE, SHARON M, WIEHE, SARAH ELIZABETH · 2018 to 2022
$27.2M
Resource CoreP30AR072581 · NIAMS · INDIANA UNIVERSITY INDIANAPOLIS · PI Sharon M Moe · 2017 to 2026
$8.3M
Indiana University Kidney Training Program (IU-KTP)T32DK120524 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI MOE, SHARON M · 2019 to 2023
$1.3M
Enhancing Fatty Acid Oxidation Will Improve Skeletal Muscle & Enable Exercise Adaptation in CKDR03DK125665 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI AVIN, KEITH G · 2020 to 2021
$238k
NCATS NIH HHS UL1 TR002529NIAMS NIH HHS P30 AR072581NIDDK NIH HHS R03 DK125665NIDDK NIH HHS T32 DK120524
6 · The paper itself

Abstract

purpose of reviewTo provide an overview of the recent literature investigating the pathophysiology of skeletal muscle changes, interventions for skeletal muscle, and effects of exercise in chronic kidney disease (CKD). RECENT

findingsThere are multiple CKD-related changes that negatively impact muscle size and function. However, the variability in the assessment of muscle size, in particular, hinders the ability to truly understand the impact it may have in CKD. Exercise interventions to improve muscle size and function demonstrate inconsistent responses that warrant further investigation to optimize exercise prescription. Despite progress in the field, there are many gaps in the knowledge of the pathophysiology of sarcopenia of CKD. Identifying these gaps will help in the design of interventions that can be tested to target muscle loss and its consequences such as impaired mobility, falls, and poor quality of life in patients with CKD.

Indexed as

Renal Insufficiency, ChronicSarcopeniaExerciseHumansMuscle, SkeletalQuality of LifeChronic kidney diseaseInflammationKlothoOxidative stressSarcopeniaSkeletal muscle fibrosisSkeletal muscle regenerationUremic toxins

Identifiers

PMID36149594
PMCPMC10064704
OpenAlexW4296794070

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.