Evidence map›Paper›PMID 36149575›Full record

ArticleJournal of clinical monitoring and computing2023

Model analysis of multiple breath nitrogen washout data: robustness to variations in breathing pattern.

Jason H T Bates, Stephen Milne, Blake M Handley, Sandra Rutting, David G Chapman, Gregory G King, Claude S Farah, Paul D Robinson, Cindy Thamrin

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of clinical monitoring and computing, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Jason H T BatesDepartment of Medicine, University Vermont, 149 Beaumont Avenue, Burlington, VT, USA. jason.h.bates@med.uvm.edu.
Stephen MilneWoolcock Institute of Medical Research, University of Sydney, Glebe, Sydney, Australia.
Blake M HandleyWoolcock Institute of Medical Research, University of Sydney, Glebe, Sydney, Australia.
Sandra RuttingWoolcock Institute of Medical Research, University of Sydney, Glebe, Sydney, Australia.
David G ChapmanWoolcock Institute of Medical Research, University of Sydney, Glebe, Sydney, Australia.
Gregory G KingWoolcock Institute of Medical Research, University of Sydney, Glebe, Sydney, Australia.
Claude S FarahWoolcock Institute of Medical Research, University of Sydney, Glebe, Sydney, Australia.
Paul D RobinsonWoolcock Institute of Medical Research, University of Sydney, Glebe, Sydney, Australia.
Cindy ThamrinWoolcock Institute of Medical Research, University of Sydney, Glebe, Sydney, Australia.
Woolcock Institute of Medical Research · AURoyal North Shore Hospital · AUUniversity of Sydney · AUUniversity of Vermont · US

Funding

Non-Allergic Late-Onset Asthma of Obesity: Pathophysiology and TherapyR01HL130847 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI BATES, JASON HT, DIXON, ANNE E · 2016 to 2019
$2.3M
NHLBI NIH HHS HL130847
6 · The paper itself

Abstract

We recently developed a model-based method for analyzing multiple breath nitrogen washout data that does not require identification of Phase-III. In the present study, we assessed the effect of irregular breathing patterns on the intra-subject variabilities of the model parameters. Nitrogen fraction at the mouth was measured in 18 healthy and 20 asthmatic subjects during triplicate performances of multiple breath nitrogen washout, during controlled (target tidal volume 1 L at 8-12 breaths per minute) and free (unrestricted) breathing. The parameters S

Indexed as

AsthmaNitrogenHumansLungRespirationRespiratory Function TestsNitrogenControlled breathingDead space volumeFunctional residual capacityPhase-IIISpontaneous breathingVentilation heterogeneity

Identifiers

PMID36149575
OpenAlexW4296793952

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.