Evidence map›Paper›PMID 36149442›Full record

ArticleInnere Medizin (Heidelberg, Germany)2022

[Paraneoplastic hyperleukocytosis in lung cancer].

Josef Heusinger, Paul Czech, Heidi Hengstler, Frank Schaumann, Anja Rückert, Frank Schmid, Jörg Kalla, Uta Diergardt, Hinrich Bremer, Paul La Rosée

Open access · bronzeAbstract readCase ReportsEnglish Abstract
In one paragraph

Article in Innere Medizin (Heidelberg, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Josef HeusingerKlinik für Innere Medizin II: Onkologie, Hämatologie, Immunologie, Infektiologie und Palliativmedizin, Schwarzwald-Baar-Klinikum, Klinikstr. 11, 78052, Villingen-Schwenningen, Deutschland. josef.heusinger@sbk-vs.de.
Paul CzechKlinik für Dermatologie und Venerologie, Universitätsklinikum Freiburg, Freiburg, Deutschland.
Heidi HengstlerKlinik für Innere Medizin II: Onkologie, Hämatologie, Immunologie, Infektiologie und Palliativmedizin, Schwarzwald-Baar-Klinikum, Klinikstr. 11, 78052, Villingen-Schwenningen, Deutschland.
Frank SchaumannKlinik für Innere Medizin II: Onkologie, Hämatologie, Immunologie, Infektiologie und Palliativmedizin, Schwarzwald-Baar-Klinikum, Klinikstr. 11, 78052, Villingen-Schwenningen, Deutschland.
Anja RückertKlinik für Innere Medizin II: Onkologie, Hämatologie, Immunologie, Infektiologie und Palliativmedizin, Schwarzwald-Baar-Klinikum, Klinikstr. 11, 78052, Villingen-Schwenningen, Deutschland.
Frank SchmidInstitut für Radiologie und Nuklearmedizin, Schwarzwald-Baar-Klinikum, Villingen-Schwenningen, Deutschland.
Jörg KallaInstitut für Pathologie, Schwarzwald-Baar-Klinikum, Villingen-Schwenningen, Deutschland.
Uta DiergardtInstitut für Pathologie, Schwarzwald-Baar-Klinikum, Villingen-Schwenningen, Deutschland.
Hinrich BremerLungenzentrum, Schwarzwald-Baar-Klinikum, Donaueschingen, Deutschland.
Paul La RoséeKlinik für Innere Medizin II: Onkologie, Hämatologie, Immunologie, Infektiologie und Palliativmedizin, Schwarzwald-Baar-Klinikum, Klinikstr. 11, 78052, Villingen-Schwenningen, Deutschland.
Schwarzwald-Baar Klinikum · DEUniversity Medical Center Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paraneoplastic leukocytosis in solid tumors is associated with poor prognosis. While mild leukocytosis is common, paraneoplastic hyperleukocytosis is extremely rare. The case of a 73-year-old male diagnosed with an adenocarcinoma of the lung and a peak white blood cell count of 178,000/µl is reported. The patient succumbed to the disease after two cycles of immunochemotherapy only 2 months after first hospital admission. Specific treatment options are still under investigation and have not been reported in clinical use.

Indexed as

LeukocytosisLung NeoplasmsAgedHumansLeukocyte CountLungMaleCarcinomaCarcinoma, non-small-cell lungGranulocyte colony-stimulating factorLeukemoid reactionParaneoplastic syndromes

Identifiers

PMID36149442
PMCPMC9510345
OpenAlexW4296807786

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.