Evidence map›Paper›PMID 36149340›Full record

ArticleThe journal of spinal cord medicine2024

Pain, pain interference, social and school/work functioning in youth with spinal cord injury: A mediation analysis.

James W Varni, Kathy Zebracki, Miriam Hwang, M J Mulcahey, Lawrence C Vogel

Abstract read
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Article in The journal of spinal cord medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

James W VarniDepartment of Pediatrics, College of Medicine, Texas A&M University, College Station, Texas, USA.ORCID 0000-0003-4816-4357
Kathy ZebrackiShriners Children's Chicago, Chicago, Illinois, USA.
Miriam HwangShriners Children's Chicago, Chicago, Illinois, USA.
M J MulcaheyDepartment of Physical Medicine, Center for Outcomes and Measurement, Jefferson College of Rehabilitation Sciences, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Lawrence C VogelShriners Children's Chicago, Chicago, Illinois, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CONTEXT/

objectiveThe objective of the present study was to investigate the effects of pain severity, pain interference and social functioning in a serial multiple mediator model predicting school/work functioning in youth with spinal cord injury (SCI) from their perspective.

designExplanatory or mechanistic study.

settingPediatric specialty hospital.

participants125 youth with SCI ages 8-24. OUTCOME MEASURES: The Pain Severity Item and Pain Interference Scale from the PedsQL™ Spinal Cord Injury Module, and the Social Functioning and School/Work Functioning Scales from the PedsQL™ 4.0 Generic Core Scales Short Form SF15 were completed.

resultsHierarchical multiple regression and serial multiple mediator model analyses were conducted to test the percent variability accounted for and the mediating effects of pain interference and social functioning in the association between pain severity and school/work functioning. Pain predictive effects on school/work functioning were serially mediated by pain interference and social functioning. In a predictive analytics model conducted with hierarchical multiple regression analysis, age, sex, pain, pain interference and social functioning accounted for 45% of the variance in youth-reported school/work functioning (P < 0.001), demonstrating a large effect size.

conclusionThe mechanisms of the predictive effects of pain severity on school/work functioning in youth with SCI are explained in part by the serial multiple mediator effects of pain interference and social functioning. Identifying the multiple mediators of SCI pain on school/work functioning from the perspective of youth with SCI may facilitate future clinical research and practice to ameliorate impaired daily functioning and improve overall well-being.

Indexed as

Spinal Cord InjuriesAdolescentAdultChildFemaleHumansMaleMediation AnalysisPainPsychosocial FunctioningYoung AdultHRQOL, health-related quality of lifePainPain interferencePedsQLPedsQL™, Pediatric Quality of Life Inventory™SchoolSCI, spinal cord injurySocialSpinal cord injury

Identifiers

PMID36149340
PMCPMC11218589

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.