Evidence map›Paper›PMID 36149001›Full record

ArticleJournal of addiction medicine

Enhancing Patient Choice: Using Self-administered Intranasal Naloxone for Novel Rapid Buprenorphine Initiation.

Adam Randall, Ilana Hull, Stephen A Martin

Registry-linked trialOpen access · hybridAbstract readCase Reports
In one paragraph

Article in Journal of addiction medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06089707 (Behavioral Pharmacological Examination of a Novel Buprenorphine Induction Method Among Individuals Who Use Fentanyl), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06089707 phase3active not recruitingnot on this map

Behavioral Pharmacological Examination of a Novel Buprenorphine Induction Method Among Individuals Who Use Fentanyl

TypeinterventionalSponsorUniversity of Maryland, BaltimoreRan2024 to 2030Enrolled3ConditionsOpioid Use DisorderArmsNaloxone Nasal Spray
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Review
  8. Ketamine-assisted buprenorphine initiation: a pilot case series.Addiction science & clinical practice · 2024
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Adam RandallFrom the Boulder Care, Portland, OR (AR, IH, SAM); University of Pittsburgh School of Medicine Medical Center, Pittsburgh, PA (IH); UMass Chan Medical School, Worcester, MA (SAM).
Ilana Hull
Stephen A Martin
Strateji Araşdırmalar Mərkəzi · AZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Buprenorphine-naloxone (BUP-NX) is a lifesaving treatment for opioid use disorder. The increasing use of illicitly manufactured fentanyl, however, has made initiating BUP-NX more likely to precipitate withdrawal-an experience that deters treatment and causes return to use. If BUP-NX cannot be successfully started, it cannot work. We describe the case of a patient who was able to transition to a therapeutic dose of BUP-NX less than 3 hours after his last illicitly manufactured fentanyl use by choosing to self-administer intranasal naloxone. After the naloxone, the transition took 31 minutes, including 14 minutes of expected moderately severe withdrawal. He remains in care with BUP-NX and would recommend this transition approach to others.

Indexed as

BuprenorphineOpioid-Related DisordersBuprenorphine, Naloxone Drug CombinationFentanylHumansMaleNaloxoneNarcotic AntagonistsOpiate Substitution TreatmentPatient PreferenceBuprenorphineBuprenorphine, Naloxone Drug CombinationFentanylNaloxoneNarcotic Antagonists

Identifiers

PMID36149001
PMCPMC10022654
OpenAlexW4296801019

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.