Evidence map›Paper›PMID 36149000›Full record

ArticleJournal of addiction medicine

A Hospital-based Managed Alcohol Program in a Canadian Setting.

Seonaid Nolan, Christopher Fairgrieve, Huiru Dong, Emma Garrod, Holly van Heukelom, Beena P Parappilly, Mark McLean, Judith I Tsui, Jeffrey H Samet

Abstract read
In one paragraph

Article in Journal of addiction medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Seonaid NolanFrom the British Columbia Centre on Substance Use, Vancouver, BC, Canada (SN, HD); Department of Medicine, University of British Columbia, St. Paul's Hospital, Vancouver, BC, Canada (SN); Department of Family and Community Medicine, University of Toronto, Toronto, ON, Canada (CF); School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada (HD); Providence Health Care, St. Paul's Hospital, Vancouver, BC, Canada (EG, HvH, BPP); Department of Family Medicine, University of British Columbia, St. Paul's Hospital, Vancouver, BC, Canada (MM); Section of General Internal Medicine, Department of Medicine, University of Washington School of Medicine, Harborview Medicine Center, Seattle, WA (JIT); and Section of General Internal Medicine, Department of Medicine, Boston University School of Medicine, Boston Medical Center, Boston, MA (JHS).
Christopher Fairgrieve
Huiru Dong
Emma Garrod
Holly van Heukelom
Beena P Parappilly
Mark McLean
Judith I Tsui
Jeffrey H Samet

Funding

Advancing Clinical Research Training within Addiction Residency ProgramsR25DA033211 · NIDA · BOSTON MEDICAL CENTER · PI Patrick O'Connor, JEFFREY H. SAMET · 2012 to 2026
$4.2M
Mentoring the next generation of addiction clinician scientists while responding to the opioid epidemicR25DA037756 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI FAIRBAIRN, NADIA · 2014 to 2023
$3.6M
NIDA NIH HHS R25 DA033211NIDA NIH HHS R25 DA037756
6 · The paper itself

Abstract

objectivesA managed alcohol program (MAP) is a harm reduction strategy that provides regularly, witnessed alcohol to individuals with a severe alcohol use disorder. Although community MAPs have positive outcomes, applicability to hospital settings is unknown. This study describes a hospital-based MAP, characterizes its participants, and evaluates outcomes.

methodsA retrospective chart review of MAP participants was conducted at an academic hospital in Vancouver, Canada, between July 2016 and October 2017. Data included demographics, alcohol/substance use, alcohol withdrawal risk, and MAP indication. Outcomes after MAP initiation included the change in mean daily alcohol consumption and liver enzymes.

resultsSeventeen patients participated in 26 hospital admissions: 76% male, mean age of 54 years, daily consumption prehospitalization of a mean 14 alcohol standard drinks, 59% reported previous nonbeverage alcohol consumption, and 41% participated in a community MAP. Most participants were high risk for severe, complicated alcohol withdrawal and presented in moderate withdrawal. Continuation of community MAP was the most common indication for hospital-based MAP initiation (38%), followed by a history of leaving hospital against medical advice (35%) and hospital illicit alcohol use (15%). Hospital-based MAP resulted in a mean of 5 fewer alcohol standard drinks daily compared with preadmission ( P = 0.002; 95% confidence interval, 2-8) and improvement in liver enzymes, with few adverse events.

conclusionsParticipation in a hospital-based MAP may be an effective safe approach to reduce harms for some individuals with severe alcohol use disorder. Further study is needed to understand who benefits most from hospital-MAP and potential benefits/harms following hospital discharge.

Indexed as

AlcoholismSubstance Withdrawal SyndromeAlcohol DrinkingCanadaFemaleHospitalsHumansMaleMiddle AgedRetrospective Studies

Identifiers

PMID36149000
PMCPMC10062701

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.