ArticleAnnals of medicine2022
Long-term outcomes and predictors of percutaneous radiofrequency thermocoagulation of Gasserian ganglion for maxillary trigeminal neuralgia: a retrospective analysis of 1070 patients with minimum 2-year follow-up.
Article in Annals of medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 8 citations in OpenAlex.
- Clinical predictors of treatment success following Gasserian ganglion conventional radiofrequency in trigeminal neuralgia: secondary cohort analysis.Journal of oral & facial pain and headache · 2026Article
- The efficacy and prognosis analysis of radiofrequency thermocoagulation and percutaneous balloon compression for recurrent trigeminal neuralgia: a retrospective study.The Korean journal of pain · 2026Article
- Nomogram prediction model for pain recurrence in patients with trigeminal neuralgia after microvascular decompression.Neurosurgical review · 2026Article
- Neurovascular Compression Syndromes of Cranial Nerves: A Multidisciplinary Guide to Management.Brain sciences · 2026Review
- Efficacy and Safety of Selective Extracranial Radiofrequency Thermocoagulation and Percutaneous Balloon Compression for V3 Trigeminal Neuralgia.Pain research & management · 2026Article
- Peripheral Branch Radiofrequency Thermocoagulation for Primary V2 Trigeminal Neuralgia: A Retrospective Cohort Study Guided by Diagnostic Nerve Blocks.Pain research & management · 2026Article
- Individualized rs-fMRI reveals brain-circuit heterogeneity and predicts early recurrence in trigeminal neuralgia.Frontiers in psychiatry · 2026Article
- Glymphatic and neurofluidic dysfunction in classical trigeminal neuralgia: a multimodal MRI study of brain-CSF functional and structural dynamics.BMC medical imaging · 2025Article
- A combination of low-temperature radiofrequency thermocoagulation and pulsed radiofrequency of the bilateral Gasserian ganglion for bilateral trigeminal neuralgia due to multiple sclerosis: a case report.JA clinical reports · 2025Article
- Microvascular Decompression versus Radiofrequency Ablation in Trigeminal Neuralgia of the Maxillary and Mandibular Divisions.Asian journal of neurosurgery · 2024Article
- The long-term outcome of CT-guided radiofrequency ablation of the peripheral branches of the trigeminal nerve in trigeminal neuralgia.Neurosurgical review · 2024Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo estimate long-term efficacy and safety for maxillary trigeminal neuralgia (TN) using radiofrequency thermocoagulation (RFT) targeted on Gasserian ganglion, and to identify the factors which may influence outcomes after procedure.
methodsFrom 2006 to 2019, 1070 patients underwent RFT for the treatment of medically refractory maxillary TN was included. All patients were followed up for at least 2 years. Outcomes and complications were recorded and analysed. Logistic regression analysis was employed to identify risk factors of long-term pain recurrence. Prognostic value was calculated from receiver-operating characteristic curve (ROC).
resultsLongitudinal analysis was taken place for 97 non-responders (9.1%) with ineffective pain relief, 253 responders (23.6%) with pain recurrence and 720 responders (67.3%) without pain recurrence. The median pain-free survival (PFS) was 112.0 months (95% CI: 107.5, 116.5). The pain-free rates were 89.9% (95% CI: 88.0-91.8%) at 1 year, 83.8% (95% CI: 81.5-86.1%) at 2 years, 75.4% (95% CI: 72.7-78.1%) at 5 years and 70.2% (95% CI: 67.4-73.0%) at 10 years. Atypical facial pain (HR = 5.373, 95% CI: 2.623-11.004,
conclusionsFavourable outcomes were achieved in terms of long-term pain relief and complications rate after RFT for maxillary TN. Patients with typical facial pain, normal facial sensation, and good initial response to medications may have favourable long-term outcomes.Key messagesThis is a retrospective analysis of radiofrequency thermocoagulation (RFT) targeted on Gasserian ganglion for the treatment of maxillary trigeminal neuralgia (TN) during long-term follow-up. Recurrence-free survival among a large sample was assessed and risk factors associated with long-term pain recurrence was identified. It has been verified that inadvertent damage of ophthalmic and mandibular division causes ophthalmic and masticatory complications. Therefore, a more precise needle tip position and thermocoagulation using a relatively low temperature was recommended.
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