Evidence map›Paper›PMID 36148868›Full record

ArticleEpidemiology and psychiatric sciences2022

Wechsler Intelligence Scale for Adults - Fourth Edition profiles of adults with autism spectrum disorder.

G Cicinelli, E Nobile, S Brighenti, S Bari, E Tonella, A Aresi, M Attanasio, M Mazza, M Valenti, R Keller

Open access · goldAbstract read
In one paragraph

Article in Epidemiology and psychiatric sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Cognitive Profile in Autism and ADHD: A Meta-Analysis of Performance on the WAIS-IV and WISC-V.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2024
    Pooled it
  2. Article
  3. Cognitive Profile of Autism and Intellectual Disorder in Wechsler's Scales: Meta-Analysis.European journal of investigation in health, psychology and education · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

G CicinelliAdult Autism Center, Mental Health Department, Local Health Unit ASL Città di Torino, Turin 10138, Italy.ORCID https://orcid.org/0000-0002-4221-888X
E NobileAdult Autism Center, Mental Health Department, Local Health Unit ASL Città di Torino, Turin 10138, Italy.
S BrighentiAdult Autism Center, Mental Health Department, Local Health Unit ASL Città di Torino, Turin 10138, Italy.
S BariAdult Autism Center, Mental Health Department, Local Health Unit ASL Città di Torino, Turin 10138, Italy.
E TonellaAdult Autism Center, Mental Health Department, Local Health Unit ASL Città di Torino, Turin 10138, Italy.
A AresiAdult Autism Center, Mental Health Department, Local Health Unit ASL Città di Torino, Turin 10138, Italy.
M AttanasioRegional Centre for Autism, Dipartimento di Scienze cliniche applicate e biotecnologiche, University of L'Aquila, L'Aquila, Italy.
M MazzaRegional Centre for Autism, Dipartimento di Scienze cliniche applicate e biotecnologiche, University of L'Aquila, L'Aquila, Italy.
M ValentiRegional Centre for Autism, Dipartimento di Scienze cliniche applicate e biotecnologiche, University of L'Aquila, L'Aquila, Italy.
R KellerDepartment of Psychology, University of Turin, Via Giuseppe Verdi, 8, 10124 Torino, TO, Italy.ORCID https://orcid.org/0000-0002-6873-9827
Torino e-district · ITUniversity of L'Aquila · ITUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimIn this study, we have compared 229 Wechsler Adults Intelligence Scale - Fourth Edition (WAIS-IV) cognitive profiles of different severity adults with autism spectrum disorder to verify the impact of several variables including sex, age, level of education and autism severity level in an Italian sample. Moreover, we wanted to find out the optimal cut points for the major intelligence quotients in order to discriminate autism severity levels.

methodsParticipants were recruited from two National Health System Center in two different Italian regions and were assessed with gold-standard instruments as a part of their clinical evaluation. According to DSM-5, cognitive domains were also measured with multi-componential tests. We used the Italian adaptation of WAIS-IV. We checked our hypotheses using linear regression models and receiver operating characteristics (ROC) curves.

resultsOur results showed that age and level of education have a strong impact on Verbal Comprehension (VCI) and Working Memory Indexes (WMI). Gender differences are relevant when considering the VCI and Processing Speed index (PSI) in which women obtained the best performance. These differences are still relevant when considering cut points of ROC because 69 resulted to be the optimal cut point for women, 65 for men.

conclusionsFew conclusions can be assumed only examining Full Scale Intelligence Quotient (FSIQ) scores as it includes many different information about broader cognitive abilities. Looking deeper at main indexes and their subtests findings are consistent with previous research on the disorder (moderate correlations of FSIQ, Perceptual Reasoning index, WMI and PSI with the participants' age), while other results are unforeseen (no effect of sex found on FSIQ score) or novel (significant effect of education on VCI and WMI). Using an algorithm predicting optimal cut point for discriminating through autism severity levels can help clinicians to better label and quantify the required help a person may need, a test cannot replace diagnostic and clinical evaluation by experienced clinicians.

Indexed as

Autism Spectrum DisorderAdultCognitionFemaleHumansIntelligence TestsMaleMemory, Short-TermWechsler ScalesAutism spectrum disorderintelligenceintelligence profileWAIS-IV

Identifiers

PMID36148868
PMCPMC9531589
OpenAlexW4296793632

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.