Evidence map›Paper›PMID 36148463›Full record

ReviewFrontiers in medicine2022

Sarcoidosis: Progression to the chronic stage and pathogenic based treatment (narrative review).

Anna Malkova, Yulia Zinchenko, Anna Starshinova, Dmitriy Kudlay, Igor Kudryavtsev, Anzhela Glushkova, Piotr Yablonskiy, Yehuda Shoenfeld

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Clinical and radiological factors affecting progression in sarcoidosis.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Anna MalkovaLaboratory of the Mosaic of Autoimmunity, St. Petersburg State University, Saint Petersburg, Russia.
Yulia ZinchenkoPhthisiopulmonology Department, St. Petersburg Research Institute of Phthisiopulmonology, Saint Petersburg, Russia.
Anna StarshinovaAlmazov National Medical Research Centre, Saint Petersburg, Russia.
Dmitriy KudlayDepartment of Pharmacology, I.M. Sechenov First Moscow State Medical University, Moscow, Russia.
Igor KudryavtsevDepartment of Immunology, Institution of Experimental Medicine, Saint Petersburg, Russia.
Anzhela GlushkovaV.M. Bekhterev National Research Medical Center for Psychiatry and Neurology, Saint Petersburg, Russia.
Piotr YablonskiyLaboratory of the Mosaic of Autoimmunity, St. Petersburg State University, Saint Petersburg, Russia.
Yehuda ShoenfeldLaboratory of the Mosaic of Autoimmunity, St. Petersburg State University, Saint Petersburg, Russia.
Saint-Petersburg Research Institute of Phthisiopulmonology · RUSt Petersburg University · RUFederal Almazov North-West Medical Research Centre · RUInstitute of Experimental Medicine · RUSechenov University · RUSt.Petersburg V.M.Bekhterev Psychoneurological Research Institute · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many factors confirm the autoimmune nature of sarcoidosis and help in determining the strategy of patient management and treatment initiation. However, the causes and the mechanisms of disease progression that result in fibrosis and insufficiency of the affected organ remain unclear. This narrative review aims to analyse the mechanisms and biomarkers of sarcoidosis progression, as well as the pathogenetic basis of sarcoidosis therapy. The following characteristics of progressive chronic sarcoidosis were revealed: the disease develops in patients with a genetic predisposition (SNP in genes GREM1, CARD15, TGF-β3, HLA-DQB1

Indexed as

adjuvantautoimmune diseasesautoimmunityfibrosisimmune therapypathogenesissarcoidosis

Identifiers

PMID36148463
PMCPMC9486475
OpenAlexW4294739790

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.