ArticleFrontiers in public health2022
The systematic analysis and 10-year prediction on disease burden of childhood cancer in China.
Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 24 citations in OpenAlex.
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- The association of tobacco use on gastrointestinal cancers: A secondary dataset analysis of the Global Burden of Disease Study 2021 and Mendelian randomization.Tobacco induced diseases · 2026Article
- Childhood cancer burden and health inequality: A systematic analysis from the global burden of diseases study 2021.PloS one · 2026Article
- Trends and projections in cause-specific mortality among patients with colorectal cancer in the United States, 1999-2040.Frontiers in public health · 2026Article
- Secondary peritoneal and retroperitoneal malignancies in the elderly: trends and disparities (1999-2022) with forecasts to 2035 from a national study.Cancer causes & control : CCC · 2025Article
- Levels of anxiety, social support and coping strategies of family members of children with acute leukemia: a cross-sectional study.BMC pediatrics · 2025Article
- Declining Myocarditis Mortality in the United States and the Impact of the COVID-19 Pandemic.Journal of clinical medicine · 2025Article
- Global, regional, and national burden for childhood and adolescent cancers from 1990 to 2021: from the Global Burden of Disease Study 2021.Pediatric surgery international · 2025Article
- Trends and Disparities in Parkinson's Disease Mortality in the United States with Predictions Using Machine Learning.NeuroSci · 2025Article
- Global burden of cancer attributable to high BMI (1990-2031): a multidimensional analysis based on GBD and Mendelian randomization.Frontiers in nutrition · 2025Article
- Temporal trend in non-melanoma skin cancer mortality in China, 1992-2021: an analysis for the global burden of disease study 2021.Frontiers in medicine · 2025Article
- Disease burden and trends of malignant neoplasm of bone and articular cartilage in childhood in China, 1990-2021 and comparison with United States and India: findings from the Global Burden of Disease Study 2021.Frontiers in public health · 2025Article
- Prediction of early-onset colorectal cancer mortality rates in the United States using machine learning.Cancer medicine · 2024Article
- The impact of parental overprotection on the emotions and behaviors of pediatric hematologic cancer patients: a multicenter cross-sectional study.Frontiers in psychology · 2023Article
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5 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Background: There is a lack of in-depth analysis regarding the disease burden of childhood cancer in China. Indeed, this is the first time the topic has been addressed in detail. Drawing on population-based data for the past 30 years, this study systematically analyzes the composition and long-term trend of this disease burden in China. Methods: GBD 2019 contained population-based data from 1990 to 2019 and was prepared using Microsoft Excel 2016. We used AAPC and ARIMA models for trend analysis and prediction formulation. Results: In 2019, there were 45,601 new cases, 9,156 cancer deaths, and 782,530 DALYs in China. From 1990 to 2019, leukemia, together with brain and CNS cancer, invariably ranked highest in terms of new cases, cancer deaths, and DALYs. Leukemia accounted for more than 50%, but decreased over time. By contrast, the proportions for brain and CNS cancer increased. There were significant decreases in the overall incidence, mortality, and DALY rates in China, but these were still higher than the corresponding global average levels. Considering all types of childhood cancer, the incidence rate of testicular cancer showed the biggest increase, and the mortality and DALY rates of leukemia showed the largest decrease. In terms of different age groups, the overall incidence rate of childhood cancers increased in 0 to 4 age group, but it decreased in 5 to 14 age groups. The overall mortality and DALY rates of childhood cancers decreased in all four age groups. Over the next 10 years, the overall incidence rate of childhood cancer will increase, but the overall mortality and DALY rates will decrease. The increase in malignant skin melanoma will comprise the largest rise in the incidence, while the decrease for leukemia will be the largest fall in the incidence, cancer deaths, and DALYs. Conclusion: The disease burden of all childhood cancers in China remains highly serious, especially for certain types of cancer and certain age groups. China should focus more emphatically on the incidence of childhood cancer in future, and it must consistently strengthen investment in the relevant research and medical resources to reduce the disease burden in this field.
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