Evidence map›Paper›PMID 36148303›Full record

ArticleFrontiers in physiology2022

Self-supervised neural network improves tri-exponential intravoxel incoherent motion model fitting compared to least-squares fitting in non-alcoholic fatty liver disease.

Marian A Troelstra, Anne-Marieke Van Dijk, Julia J Witjes, Anne Linde Mak, Diona Zwirs, Jurgen H Runge, Joanne Verheij, Ulrich H Beuers, Max Nieuwdorp, Adriaan G Holleboom and 2 more

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Article in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Marian A TroelstraDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, Amsterdam, Netherlands.
Anne-Marieke Van DijkDepartment of Vascular Medicine, Amsterdam UMC, Amsterdam, Netherlands.
Julia J WitjesDepartment of Vascular Medicine, Amsterdam UMC, Amsterdam, Netherlands.
Anne Linde MakDepartment of Vascular Medicine, Amsterdam UMC, Amsterdam, Netherlands.
Diona ZwirsDepartment of Vascular Medicine, Amsterdam UMC, Amsterdam, Netherlands.
Jurgen H RungeDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, Amsterdam, Netherlands.
Joanne VerheijDepartment of Pathology, Amsterdam UMC, Amsterdam, Netherlands.
Ulrich H BeuersDepartment of Gastroenterology and Hepatology, Amsterdam UMC, Amsterdam, Netherlands.
Max NieuwdorpDepartment of Vascular Medicine, Amsterdam UMC, Amsterdam, Netherlands.
Adriaan G HolleboomDepartment of Vascular Medicine, Amsterdam UMC, Amsterdam, Netherlands.
Aart J NederveenDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, Amsterdam, Netherlands.
Oliver J Gurney-ChampionDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, Amsterdam, Netherlands.
Amsterdam University Medical Centers · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent literature suggests that tri-exponential models may provide additional information and fit liver intravoxel incoherent motion (IVIM) data more accurately than conventional bi-exponential models. However, voxel-wise fitting of IVIM results in noisy and unreliable parameter maps. For bi-exponential IVIM, neural networks (NN) were able to produce superior parameter maps than conventional least-squares (LSQ) generated images. Hence, to improve parameter map quality of tri-exponential IVIM, we developed an unsupervised physics-informed deep neural network (IVIM

Indexed as

deep learningdiffusion magnetic resonance imagingintravoxel incoherent motion (IVIM)magnetic resonance imagingnon-alcoholic fatty liver diseasetri-exponentialunsupervised learning

Identifiers

PMID36148303
PMCPMC9485997
OpenAlexW4294719294

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.