Evidence map›Paper›PMID 36148260›Full record

ArticleCJC open2022

Very Early Progression of an In-Stent Calcified Nodule 2 Weeks After Drug-Eluting Stent Implantation in the Calcified Lesion.

Naoko Higashino, Takayuki Ishihara, Osamu Iida, Takuya Tsujimura, Yosuke Hata, Taku Toyoshima, Sho Nakao, Toshiaki Mano

Open access · goldAbstract readCase Reports
In one paragraph

Article in CJC open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Deep dive into intravascular coronary imaging in calcified lesions.Cardiovascular intervention and therapeutics · 2025
    Review
  3. Sailing in Dark Waters: The Challenging Management of Recurrent In-Stent Calcified Nodule Protrusion.Journal of the Society for Cardiovascular Angiography & Interventions · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Naoko HigashinoKansai Rosai Hospital Cardiovascular Center, Amagasaki, Japan.
Takayuki IshiharaKansai Rosai Hospital Cardiovascular Center, Amagasaki, Japan.
Osamu IidaKansai Rosai Hospital Cardiovascular Center, Amagasaki, Japan.
Takuya TsujimuraKansai Rosai Hospital Cardiovascular Center, Amagasaki, Japan.
Yosuke HataKansai Rosai Hospital Cardiovascular Center, Amagasaki, Japan.
Taku ToyoshimaKansai Rosai Hospital Cardiovascular Center, Amagasaki, Japan.
Sho NakaoKansai Rosai Hospital Cardiovascular Center, Amagasaki, Japan.
Toshiaki ManoKansai Rosai Hospital Cardiovascular Center, Amagasaki, Japan.
Kansai Rosai Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In-stent calcified nodules (CNs) are one of the mechanisms of in-stent restenosis, but their underlying cause has not been elucidated. We report a case of a patient with early stent thrombosis due to an in-stent CN only 2 weeks after drug-eluting stent implantation. The fact that the in-stent CN was detected only 2 weeks after the initial percutaneous coronary intervention means that the underlying mechanism was the progression of the CN, indicating that in-stent CNs can occur even in the subacute phase. After percutaneous coronary intervention for a severe calcified lesion, very early progression of CNs can occur, and they require close follow-up and intensive antiplatelet therapy.

Identifiers

PMID36148260
PMCPMC9486871
OpenAlexW4284991240

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.