Evidence map›Paper›PMID 36148054›Full record

ReviewFrontiers in cardiovascular medicine2022

SlicerHeart: An open-source computing platform for cardiac image analysis and modeling.

Andras Lasso, Christian Herz, Hannah Nam, Alana Cianciulli, Steve Pieper, Simon Drouin, Csaba Pinter, Samuelle St-Onge, Chad Vigil, Stephen Ching and 4 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Andras LassoLaboratory for Percutaneous Surgery, School of Computing, Queen's University, Kingston, ON, Canada.
Christian HerzDepartment of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Hannah NamDepartment of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Alana CianciulliDepartment of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Steve PieperIsomics, Inc., Boston, MA, United States.
Simon DrouinSoftware and Information Technology Engineering, École de Technologie Supérieure, Montreal, QC, Canada.
Csaba PinterPixel Medical, Kingston, ON, Canada.
Samuelle St-OngeSoftware and Information Technology Engineering, École de Technologie Supérieure, Montreal, QC, Canada.
Chad VigilDepartment of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Stephen ChingDepartment of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Kyle SunderlandLaboratory for Percutaneous Surgery, School of Computing, Queen's University, Kingston, ON, Canada.
Gabor FichtingerLaboratory for Percutaneous Surgery, School of Computing, Queen's University, Kingston, ON, Canada.
Ron KikinisDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Matthew A JolleyDepartment of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Children's Hospital of Philadelphia · USQueen's University · CAÉcole de Technologie Supérieure · CABrigham and Women's Hospital · US

Funding

Computer Modeling of the Tricuspid Valve in Hypoplastic Left Heart SyndromeR01HL153166 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI JOLLEY, MATTHEW · 2020 to 2024
$3.7M
NHLBI NIH HHS R01 HL153166
6 · The paper itself

Abstract

Cardiovascular disease is a significant cause of morbidity and mortality in the developed world. 3D imaging of the heart's structure is critical to the understanding and treatment of cardiovascular disease. However, open-source tools for image analysis of cardiac images, particularly 3D echocardiographic (3DE) data, are limited. We describe the rationale, development, implementation, and application of SlicerHeart, a cardiac-focused toolkit for image analysis built upon 3D Slicer, an open-source image computing platform. We designed and implemented multiple Python scripted modules within 3D Slicer to import, register, and view 3DE data, including new code to volume render and crop 3DE. In addition, we developed dedicated workflows for the modeling and quantitative analysis of multi-modality image-derived heart models, including heart valves. Finally, we created and integrated new functionality to facilitate the planning of cardiac interventions and surgery. We demonstrate application of SlicerHeart to a diverse range of cardiovascular modeling and simulation including volume rendering of 3DE images, mitral valve modeling, transcatheter device modeling, and planning of complex surgical intervention such as cardiac baffle creation. SlicerHeart is an evolving open-source image processing platform based on 3D Slicer initiated to support the investigation and treatment of congenital heart disease. The technology in SlicerHeart provides a robust foundation for 3D image-based investigation in cardiovascular medicine.

Indexed as

3D echocardiography (3DE)cardiac valvescomputer modeling (simulation)image-based modelingopen-sourcepediatric cardiology and surgery

Identifiers

PMID36148054
PMCPMC9485637
OpenAlexW4294711935

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.