Evidence map›Paper›PMID 36148008›Full record

ArticleFrontiers in molecular biosciences2022

Adamts10 controls transforming growth factor

Lauren K Wareham, Amy E Whitener, Hang-Jing Wu, Shu-Yu Wu, Hassane S Mchaourab, Douglas P Mortlock, Rachel W Kuchtey, John Kuchtey

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular biosciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Optic neuropathy associated with TGFβ dysregulation in mice with a glaucoma-causative mutation of ADAMTS10.Matrix biology : journal of the International Society for Matrix Biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Lauren K WarehamVanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, TN, United States.
Amy E WhitenerVanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, TN, United States.
Hang-Jing WuVanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, TN, United States.
Shu-Yu WuDepartment of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, United States.
Hassane S MchaourabDepartment of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, United States.
Douglas P MortlockDepartment of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, United States.
Rachel W KuchteyVanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, TN, United States.
John KuchteyVanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, TN, United States.
Vanderbilt University · USVanderbilt University Medical Center · US

Funding

MOLECULAR BASIS OF LENS TRANSPARENCYR01EY012018 · NEI · VANDERBILT UNIVERSITY · PI MCHAOURAB, HASSANE S · 2003 to 2023
$10.4M
Investigation of ADAMTS in glaucoma pathogenesisR01EY027746 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KUCHTEY, JOHN G · 2017 to 2021
$1.9M
NEI NIH HHS R01 EY012018NEI NIH HHS R01 EY027746
6 · The paper itself

Abstract

Although mutations in

Indexed as

ADAMTS10morpholino (MO)retinaretinal developmentretinal ganglion cell (RGC)transforming growth factor beta (TGFβ)zebrafish

Identifiers

PMID36148008
PMCPMC9485804
OpenAlexW4294713101

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.