ReviewIJID regions2022
HIV and adolescent girls and young women in sub-Saharan Africa: A call for expedited action to reduce new infections.
Review in IJID regions, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 103 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
103 citing papers in PubMed, 4 syntheses or guidelines pooled it, 141 citations in OpenAlex.
- HIV vulnerability among adolescent girls and young women in sub-Saharan Africa: a systematic review of individual social and structural determinants.BMC public health · 2026Pooled it
- Knowledge of reproductive-age women about mother-to-child transmission of HIV and associated factors: a systematic review and meta-analysis.Systematic reviews · 2026Pooled it
- A systematic review of the effectiveness of participatory, health system-based interventions to improve the sexual and reproductive health and rights of adolescent girls and young women in Sub-Saharan Africa.Sexual and reproductive health matters · 2025Pooled it
- Preferences for Long-Acting HIV Pre-Exposure Prophylaxis among Women of Reproductive Age in Low- and Middle-income Countries: A Systematic Review.AIDS and behavior · 2025Pooled it
- Trial
- Higher Acceptability of the Monthly Dapivirine Ring Versus Daily Oral Pre-Exposure Prophylaxis Among Adolescent Girls and Young Women in Sub-Saharan Africa in the REACH Trial.Journal of acquired immune deficiency syndromes (1999) · 2025Trial
- Engagement of adolescent girls and young women into an early oral PrEP open-label study in Southern Africa: lessons learned from HPTN 082.BMC public health · 2025Trial
- Acceptability of an annual tenofovir alafenamide implant for HIV prevention in South African women: findings from the CAPRISA 018 Phase I clinical trial.Journal of the International AIDS Society · 2025Trial
- Correlates of willingness to use pre-exposure prophylaxis (PrEP) among young people impacted by HIV in Uganda.AIDS care · 2026Article
- Scaling pleasure-based sexual and reproductive health: an impact and economic modelling study in 99 low- and middle-income countries.BMJ global health · 2026Article
- Exploring Adolescent Girls' and Young Women's Perceptions of HIV Prevention Pre-exposure Prophylaxis Use: A Qualitative Synthesis of Evidence from Sub-Saharan Africa.AIDS and behavior · 2026Review
- A Systematic Review of Barriers and Facilitators to the Uptake and Adherence of Injectable PrEP Among Adolescent Girls and Young Women in Sub-Saharan Africa.AIDS and behavior · 2026Review
- Educational Attainment and HIV Prevalence by Age Among Pregnant Women in South Africa.AIDS and behavior · 2026Article
- Transactional Sex, HIV Testing and Receipt of Results Among Adolescents and Young Women: A Comparative DHS Analysis of the Four Major Regions in Uganda.AIDS and behavior · 2026Article
- Barriers to access and use of sexual reproductive health and human immunodeficiency virus services among adolescent girls and young women in Maputo City, Mozambique.African journal of reproductive health · 2026Article
- Structural determinants of HIV inequities in South Africa: Policy analysis of the national strategic plan for HIV 2023-2028.Health policy OPEN · 2026Article
- A General Framework for Designing and Evaluating Active-Controlled Trials with Non-Inferiority Objectives.Statistics in medicine · 2026Article
- Associations Between Extreme Weather Events, Resource Insecurities, and HIV Vulnerabilities Among Adolescent Girls and Young Women in Kenya: Latent Profile Analysis Findings.AIDS and behavior · 2026Article
- Pharmacokinetics, Pharmacodynamics, Efficacy and Drug Resistance Selection of Injectable Long-Acting Lenacapavir Pre-Exposure Prophylaxis (PrEP) Against HIV.CPT: pharmacometrics & systems pharmacology · 2026Article
- Self-Care from Anywhere: Evaluating the usability of an AI-powered HIV toolkit among adolescent girls and young women and healthcare providers in South Africa.medRxiv : the preprint server for health sciences · 2026Article
43 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adolescent girls and young women (AGYW) from sub-Saharan Africa (SSA), aged 15-24, remain at substantial risk of acquiring HIV. AGYW accounted for 63% of all new HIV infections in 2021. Reducing incident infections in AGYW and among the other key populations is key to eliminating HIV infections. Expedited prioritization and actions to reduce incident infections among AGYW from sub-Saharan Africa are therefore required to attain the UNAIDS 95-95-95 targets by 2030. In this article, we discuss the factors contributing to higher HIV infections among AGYW and strategies that can be used to reduce HIV infection among them. Several biological, socio-economic, religious, and cultural factors continue to put the AGYW at a disproportionately high risk of acquiring HIV. Many AGYW in SSA are economically marginalized and therefore are unable to negotiate condom use and monogamy. Patriarchal culture predominant in SSA also exacerbates AGYW's inferiority in sexual matters. To address these factors, a multi-pronged approach is required. Some of the strategies we recommend are passing stricter sentences for sexual offenders and abusers, economically empowering AGYW, increasing the provision of sexual and reproductive health and rights (SRHR) education and services to AGYW, increasing access to pre-exposure and post-exposure prophylaxis, treatment of HIV as prevention, and engaging and educating communities on SRHR matters.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.