Evidence map›Paper›PMID 36147826›Full record

ArticlePHAGE (New Rochelle, N.Y.)2020

Bacteriophage Therapy as a Potential Management Option for Surgical Wound Infections.

L Nadareishvili, N Hoyle, N Nakaidze, D Nizharadze, M Kutateladze, N Balarjishvili, E Kutter, N Pruidze

Open access · diamondAbstract read
In one paragraph

Article in PHAGE (New Rochelle, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

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  8. Phage therapy: a promising approach forJournal of virology · 2025
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  14. Phage Therapy Against Antibiotic-Resistant and Multidrug-Resistant Infections Involving Nonhealing Wounds and Prosthetic Joint Infections Associated With Biofilms: A Mini-Review.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

L NadareishviliEliava Phage Therapy Center, Eliava Foundation, Tbilisi, Georgia.
N HoyleEliava Phage Therapy Center, Eliava Foundation, Tbilisi, Georgia.
N NakaidzePhageBiotics Research Foundation, The Evergreen State College, Olympia, Washington, USA.
D NizharadzeEliava Phage Therapy Center, Eliava Foundation, Tbilisi, Georgia.
M KutateladzeG. Eliava Institute of Bacteriophages, Microbiology and Virology, Tbilisi, Georgia.
N BalarjishviliG. Eliava Institute of Bacteriophages, Microbiology and Virology, Tbilisi, Georgia.
E KutterPhageBiotics Research Foundation, The Evergreen State College, Olympia, Washington, USA.
N PruidzeEliava Phage Therapy Center, Eliava Foundation, Tbilisi, Georgia.
George Eliava Institute of Bacteriophage, Microbiology and Virology · GE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To investigate the potential role of bacteriophages in the treatment of surgical infections, we conducted a retrospective analysis of four surgical patients who have sought treatment at the Eliava Phage Therapy Center, Tbilisi, Georgia. Two patients had chronic osteomyelitis, one presented with a diabetic foot ulcer, and the fourth patient had developed a severe infectious complication after skin grafting surgery. Patients were treated with different combinations of bacteriophage preparations, based on the sensitivity of the isolated bacterial strain toward commercially available bacteriophages. The treatment lasted on average for 1 month, and positive results were obtained in all four cases: the wounds have healed, the general health status of the patients has improved. No allergic or adverse reactions have been observed throughout the treatment.

Indexed as

antibiotic resistancebacteriophageEliavaphage therapysurgical infectionswound healing

Identifiers

PMID36147826
PMCPMC9041461
OpenAlexW3113193663

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.