Evidence map›Paper›PMID 36147789›Full record

ArticleAmerican journal of cardiovascular disease2022

Impact of achieving euthyroidism on pulmonary artery systolic pressures in hyperthyroidism-associated pulmonary hypertension - a systematic review.

Shireen R Chacko, Pradhum Ram, Tamaryn Fox, Naveen Sooknanan, Kevin Bryan Lo, Ritesh G Menezes, Savita Lasrado, Glenn Eiger, Anjali Vaidya

Open access · greenAbstract read
In one paragraph

Article in American journal of cardiovascular disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Shireen R ChackoDepartment of Medicine, Albert Einstein Medical Center Philadelphia PA, United States of America.
Pradhum RamDivision of Cardiology, Emory University Hospital Atlanta, GA, United States of America.
Tamaryn FoxDepartment of Medicine, Albert Einstein Medical Center Philadelphia PA, United States of America.
Naveen SooknananDepartment of Medicine, Albert Einstein Medical Center Philadelphia PA, United States of America.
Kevin Bryan LoDepartment of Medicine, Albert Einstein Medical Center Philadelphia PA, United States of America.
Ritesh G MenezesDepartment of Pathology, College of Medicine, King Fahd Hospital of The University, Imam Abdulrahman Bin Faisal University Dammam, Saudi Arabia.
Savita LasradoDepartment of Otorhinolaryngology and Head & Neck Surgery, Father Muller Medical College Mangalore, India.
Glenn EigerDepartment of Medicine, Albert Einstein Medical Center Philadelphia PA, United States of America.
Anjali VaidyaDivision of Cardiology, Temple University Hospital Philadelphia, PA, United States of America.
Einstein Medical Center Philadelphia · USEmory University Hospital · USFather Muller Medical College Hospital · INKing Fahd Hospital of the University · SATemple University Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this systematic review, we seek to clarify the impact of treatment of hyperthyroidism on pulmonary hypertension in patients with both these conditions. We included 39 of 709 articles retrieved, that studied patients with hyperthyroidism and pulmonary hypertension (PH). From these, those with a documented pre-treatment Pulmonary Artery Systolic Pressure (PASP) > 35 mmHg and complete follow up were analyzed, yielding 3 case series and 22 case reports with a total of 81 cases. A significant improvement in PASP was noted with achieving euthyroidism in the 3 case series. The case reports showed a significant reduction in mean PASP from 60.5 ± 13.2 mmHg to 37.5 ± 10.1 mmHg (p < 0.001) in patients with Grave's disease with achieving euthyroidism. No deaths were reported during the follow up period. Achievement of a euthyroid state in patients with hyperthyroidism is associated with statistically significant reductions in PASP.

Indexed as

Hyperthyroidismpulmonary hypertension

Identifiers

PMID36147789
PMCPMC9490158
OpenAlexW4296793790

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.