Evidence map›Paper›PMID 36147707›Full record

ArticleClinical kidney journal2022

BNT162b2 vaccine effectiveness in chronic kidney disease patients-an observational study.

Dana Bielopolski, Gilad Libresco, Noam Barda, Noa Dagan, Tali Steinmetz, Dafna Yahav, David M Charytan, Ran D Balicer, Benaya Rozen-Zvi

Open access · goldAbstract read
In one paragraph

Article in Clinical kidney journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Dana BielopolskiDepartment of Nephrology and Hypertension, Rabin Medical Center, Petah-Tikva, Israel.ORCID https://orcid.org/0000-0001-9476-0032
Gilad LibrescoClalit Research Institute, Innovation Division, Clalit Health Services, Tel Aviv, Israel.
Noam BardaARC Innovation Center, Sheba Medical Center, Ramat-Gan, Israel.ORCID https://orcid.org/0000-0002-3400-235X
Noa DaganClalit Research Institute, Innovation Division, Clalit Health Services, Tel Aviv, Israel.
Tali SteinmetzDepartment of Nephrology and Hypertension, Rabin Medical Center, Petah-Tikva, Israel.
Dafna YahavSackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.ORCID https://orcid.org/0000-0003-3181-9791
David M CharytanNephrology Division, New York University Langone Medical Center and Grossman School of Medicine, New York, NY, USA.
Ran D BalicerClalit Research Institute, Innovation Division, Clalit Health Services, Tel Aviv, Israel.
Benaya Rozen-ZviDepartment of Nephrology and Hypertension, Rabin Medical Center, Petah-Tikva, Israel.
Tel Aviv University · ILBen-Gurion University of the Negev · ILClalit Health Services · ILNYU Langone Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Chronic kidney disease (CKD) is a risk factor for severe coronavirus disease 2019 (COVID-19). We aimed to evaluate the real-life effectiveness of the BNT162b2 messenger RNA vaccine for a range of outcomes in patients with CKD compared with matched controls. Methods: Data from Israel's largest healthcare organization were retrospectively used. Vaccinated CKD [estimated glomerular filtration rate (eGFR) <60 ml/min/1.73 m Results: There were 67 861 CKD patients not treated with dialysis, 2606 hemodialysis (HD) patients and 70 467 matched controls. The risk of severe disease {RR 1.84 [95% confidence interval (CI) 0.95-2.67]} and death [RR 2.00 (95% CI 0.99-5.20)] was increased in nondialysis CKD patients compared with controls without CKD following vaccination. For the subgroup of patients with eGFR <30 ml/min/1.73 m Conclusion: Two doses of the BNT162b2 vaccine were found to be less efficient for patients with eGFR <30 ml/min/1.73 m

Indexed as

BNT162b2 vaccinechronic kidney diseaseCOVID-19

Identifiers

PMID36147707
PMCPMC9384353
OpenAlexW4283805672

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.