Evidence map›Paper›PMID 36147606›Full record

ArticleAmerican journal of blood research2022

Al-hijamah (the triple S treatment of prophetic medicine) significantly increases CD4/CD8 ratio in thalassemic patients via increasing TAC/MDA ratio: a clinical trial.

Mohamed El-Shanshory, Nahed Mohammed Hablas, Rehab El-Tahlawi, Shereen Awny, Moutasem Salih Aboonq, Soad K Al Jaouni, Tamer Mohamed Abdel-Latif, Abdelhady Ragab Abdel-Gawad, Ahmed M Okashah, Ahmed R Fakhreldin and 13 more

Open access · greenAbstract read
In one paragraph

Article in American journal of blood research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 11 institutions in 2 countries.

Mohamed El-ShanshoryProphetic Medicine Course and Research, Taibah College of Medicine Al-Madinah Al-Munawwarah, Saudi Arabia.
Nahed Mohammed HablasDepartment of Paediatrics, Tanta University Faculty of Medicine Tanta, Gharbia, Egypt.
Rehab El-TahlawiDepartment of Microbiology and Immunology, Zagazig Faculty of Medicine, Zagazig University Zagazig, Al-Sharkiyah, Egypt.
Shereen AwnyDepartment of Internal Medicine, Tanta University Faculty of Medicine Tanta, Gharbia, Egypt.
Moutasem Salih AboonqDepartment of Physiology, Taibah College of Medicine Al-Madinah Al-Munawwarah, Saudi Arabia.
Soad K Al JaouniYAJ Chair for Prophetic Medicine Applications, King Abdul-Aziz College of Medicine Jeddah, Saudi Arabia.
Tamer Mohamed Abdel-LatifDepartment of Clinical Pathology, Sohag Faculty of Medicine, Sohag University Sohag, Egypt.
Abdelhady Ragab Abdel-GawadDepartment of Clinical Pathology, Sohag Faculty of Medicine, Sohag University Sohag, Egypt.
Ahmed M OkashahAcademic Affairs Director and Consultant Clinical Immunologist, Al-Madinah Directorate of Health, Ministry of Health Al-Madinah Al-Munawwarah, Saudi Arabia.
Ahmed R FakhreldinDepartment of Paediatrics, Aswan Faculty of Medicine, Aswan University Aswan, Egypt.
Hussam BaghdadiDepartment of Clinical Biochemistry and Molecular Medicine, Taibah Faculty of Medicine, Taibah University Al-Madinah Al-Munawwarah, Saudi Arabia.
Hassan El-AllafDepartment of Medical Physiology, Sohag Faculty of Medicine, Sohag University Egypt.
Yasmin ShebelDepartment of Paediatrics, Tanta University Faculty of Medicine Tanta, Gharbia, Egypt.
Samer A El-SawyDepartment of Medical Biochemistry, Sohag Faculty of Medicine, Sohag University Egypt.
Amal AlbeihanyDepartment of Haematology, King Faisal Specialist Hospital and Research Center Al-Madinah Al-Munawwarah, Saudi Arabia.
Hany Salah MahmoudScientific Center for Experimental and Research Studies Cairo, Egypt.
Anwar A SayedDepartment of Medical Microbiology and Immunology, College of Medicine, Taibah University Al-Madinah Al-Munawwarah, Saudi Arabia.
Mostafa Am Abu-ElnagaDepartment of Anatomy and Embryology, College of Medicine, Al-Rayyan Colleges Al-Madinah Al-Munwwarah, Saudia Arabia.
Manal Mohamed Helmy NaboPaediatrics Department, Al-Rayyan Medical Colleges Al-Madinah Al-Munawwarah, Saudi Arabia.
Amr El-DardearProphetic Medicine Course and Research, Taibah College of Medicine Al-Madinah Al-Munawwarah, Saudi Arabia.
Ibrahim M Abdel-RahmanDepartment of Surgery, Al-Rayyan Medical Colleges Al-Madinah Al-Munawwarah, Saudi Arabia.
Salah Mohamed El SayedProphetic Medicine Course and Research, Taibah College of Medicine Al-Madinah Al-Munawwarah, Saudi Arabia.
Ahmed Alamir MahmoudDepartment of Medical Biochemistry, Sohag Faculty of Medicine, Sohag University Egypt.
Sohag University · EGTaibah University · SATanta University · EGRoyal Commission Medical Center · SAAcademy of Scientific Research and Technology · EGAswan University · EGImam Abdulrahman Al Faisal Hospital · SAIslamic University of Madinah · SAKing Abdul Aziz University Hospital · SAYanbu University College · SAZagazig University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Beta thalassemia is associated with decreased immunity possibly due to iron overload. Al-hijamah (Hijamah) is wet cupping therapy (WCT) of prophetic medicine. Prophet Muhammad Peace be upon him said: "The best among your treatments is Al-hijamah". Al-hijamah is a promising excretory treatment to clear blood of causative pathological substances. Al-hijamah is a three-step technique (skin suction, scarification and suction) i.e. triple S technique). Recently, we introduced Al-hijamah as a novel iron excretion therapy (through pressure-dependent filtration then excretion via the skin dermal capillaries) that significantly decreased serum iron overload and related oxidative stress using a physiological excretory mechanism (Taibah mechanism). Iron overload was reported to impair both humoral immunity and cell mediated immunity in patients with beta thalassemia. In this study, twenty patients having β-thalassemia major (maintained on iron chelation therapy) underwent a single session of Al-hijamah (30-60 minutes) using 4-5 sucking cups only. Another age and sex-matched control group of thalassemic patients received iron chelation therapy only. Al-hijamah enhanced the immunity of thalassemic patients in the form of increased CD4

Indexed as

Al-hijamahAl-hijamah indicesCD4CD8iron chelation therapyThalassemia

Identifiers

PMID36147606
PMCPMC9490105
OpenAlexW4296810026

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.