Evidence map›Paper›PMID 36147573›Full record

ReviewFrontiers in endocrinology2022

The endocrine pancreas during exercise in people with and without type 1 diabetes: Beyond the beta-cell.

Olivia McCarthy, Signe Schmidt, Merete Bechmann Christensen, Stephen C Bain, Kirsten Nørgaard, Richard Bracken

Abstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Single-Cell RNA Sequencing Shows Exercise ProtectsJournal of diabetes research · 2025
    Article
  3. Review
  4. Editorial: Integrative exercise endocrinology.Frontiers in endocrinology · 2023
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Olivia McCarthyApplied Sport, Technology, Exercise and Medicine Research Centre, Swansea University, Swansea, United Kingdom.
Signe SchmidtSteno Diabetes Center Copenhagen, Copenhagen University Hospital, Herlev, Denmark.
Merete Bechmann ChristensenSteno Diabetes Center Copenhagen, Copenhagen University Hospital, Herlev, Denmark.
Stephen C BainMedical School, Swansea University, Swansea, United Kingdom.
Kirsten NørgaardSteno Diabetes Center Copenhagen, Copenhagen University Hospital, Herlev, Denmark.
Richard BrackenApplied Sport, Technology, Exercise and Medicine Research Centre, Swansea University, Swansea, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although important for digestion and metabolism in repose, the healthy endocrine pancreas also plays a key role in facilitating energy transduction around physical exercise. During exercise, decrements in pancreatic β-cell mediated insulin release opposed by increments in α-cell glucagon secretion stand chief among the hierarchy of glucose-counterregulatory responses to decreasing plasma glucose levels. As a control hub for several major glucose regulatory hormones, the endogenous pancreas is therefore essential in ensuring glucose homeostasis. Type 1 diabetes (T1D) is pathophysiological condition characterised by a destruction of pancreatic β-cells resulting in pronounced aberrations in glucose control. Yet

Indexed as

Diabetes Mellitus, Type 1Glucagon-Secreting CellsIslets of LangerhansBlood GlucoseExerciseGlucagonGlucoseHumansInsulinMaleBlood GlucoseGlucagonGlucoseInsulinendocrine pancreasexercisepancreatic hormonesphysical activitytype 1 diabetes

Identifiers

PMID36147573
PMCPMC9485437

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.