Evidence map›Paper›PMID 36147309›Full record

ArticleProceedings. IEEE International Symposium on Biomedical Imaging2022

INVESTIGATING THE EFFECT OF TAU DEPOSITION AND APOE ON HIPPOCAMPAL MORPHOMETRY IN ALZHEIMER'S DISEASE: A FEDERATED CHOW TEST MODEL.

Jianfeng Wu, Yi Su, Eric M Reiman, Richard J Caselli, Kewei Chen, Paul M Thompson, Junwen Wang, Yalin Wang

Open access · greenAbstract read
In one paragraph

Article in Proceedings. IEEE International Symposium on Biomedical Imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Jianfeng WuSCAI, ASU, Tempe, AZ, USA.
Yi SuBAI, Phoenix, AZ, USA.
Eric M ReimanBAI, Phoenix, AZ, USA.
Richard J CaselliDept. of Neurology, Mayo Clinic, Scottsdale, AZ, USA.
Kewei ChenBAI, Phoenix, AZ, USA.
Paul M ThompsonINI, USC, Marina del Rey, CA, USA.
Junwen WangDept. of Health Sciences Research & Center for Individualized Medicine, Mayo Clinic, Scottsdale, AZ, USA.
Yalin WangSCAI, ASU, Tempe, AZ, USA.
Azerbaijan Social Work Public Union · AZArizona State University · USMayo Clinic in Arizona · USMarina Del Rey Hospital · US

Funding

Research Education ComponentP30AG019610 · NIA · SUN HEALTH RESEARCH INSTITUTE · PI REIMAN, ERIC MICHAEL · 2001 to 2020
$32.5M
APOE in the Predisposition to, Protection from and Prevention of Alzheimer's DiseaseR01AG069453 · NIA · BANNER HEALTH · PI ASHTON, NICHOLAS, LANGBAUM, JESSICA BROOKE · 2020 to 2025
$27.4M
Research Education ComponentP30AG072980 · NIA · BANNER HEALTH · PI Nicholas Ashton · 2021 to 2026
$24.9M
Ultrascale Machine Learning to Empower Discovery in Alzheimers Disease BiobanksU01AG068057 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Christos Davatzikos, Heng Huang · 2020 to 2026
$20.7M
Early joint cranial and brain development from fetal and pediatric imagingR01DE030286 · NIDCR · CHILDREN'S HOSPITAL OF LOS ANGELES · PI LEPORE, NATASHA, LINGURARU, MARIUS GEORGE · 2021 to 2025
$3.5M
Predicting the early childhood outcomes of preterm brain shape abnormalitiesR01EB025032 · NIBIB · CHILDREN'S HOSPITAL OF LOS ANGELES · PI LEPORE, NATASHA · 2017 to 2020
$2.6M
Hierarchical Bayesian Analysis of Retinotopic Maps of the Human Visual Cortex with Conformal GeometryR01EY032125 · NEI · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI LU, ZHONG-LIN, WANG, YALIN · 2021 to 2024
$1.2M
Discover and Analyze Germline-Somatic Interactions in CancerR01LM013438 · NLM · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI LIU, LI, YANG, PING · 2021 to 2023
$1.0M
Developing a Univariate Neurodegeneration Imaging Biomarker with Optimal TransportationR21AG065942 · NIA · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI WANG, YALIN · 2020 to 2020
$445k
NEI NIH HHS R01 EY032125NIA NIH HHS P30 AG019610NIA NIH HHS P30 AG072980NIA NIH HHS R01 AG069453NIA NIH HHS R21 AG065942NIA NIH HHS U01 AG068057NIBIB NIH HHS R01 EB025032NIDCR NIH HHS R01 DE030286NLM NIH HHS R01 LM013438
6 · The paper itself

Abstract

Alzheimer's disease (AD) affects more than 1 in 9 people age 65 and older and becomes an urgent public health concern as the global population ages. Tau tangle is the specific protein pathological hallmark of AD and plays a crucial role in leading to dementia-related structural deformations observed in magnetic resonance imaging (MRI) scans. The volume loss of hippocampus is mainly related to the development of AD. Besides, apolipoprotein E (

Indexed as

Alzheimer’s DiseaseAPOEfederated chow testHippocampal Morphometrytau deposition

Identifiers

PMID36147309
PMCPMC9491515
OpenAlexW4224986488

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.