Evidence map›Paper›PMID 36147217›Full record

ArticleJAAD international2022

Itch in patients with cutaneous T-cell lymphoma as a quality of life indicator.

Rosanne Ottevanger, Sylvia van Beugen, Andrea W M Evers, Rein Willemze, Maarten H Vermeer, Koen D Quint

Open access · goldAbstract read
In one paragraph

Article in JAAD international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Patient-Reported Outcome Measures (PROMS) in Lymphoma.Current oncology (Toronto, Ont.) · 2025
    Pooled it
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  16. Differential Response of Mycosis Fungoides Cells to Vorinostat.International journal of molecular sciences · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Rosanne OttevangerDepartment of Dermatology, Leiden University Medical Center, Leiden, the Netherlands.
Sylvia van BeugenInstitute of Psychology, Health, Medical and Neuropsychology Unit, Leiden University, Leiden, the Netherlands.
Andrea W M EversInstitute of Psychology, Health, Medical and Neuropsychology Unit, Leiden University, Leiden, the Netherlands.
Rein WillemzeDepartment of Dermatology, Leiden University Medical Center, Leiden, the Netherlands.
Maarten H VermeerDepartment of Dermatology, Leiden University Medical Center, Leiden, the Netherlands.
Koen D QuintDepartment of Dermatology, Leiden University Medical Center, Leiden, the Netherlands.
Leiden University Medical Center · NLLeiden University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cutaneous T-cell lymphoma (CTCL) is a chronic and progressive disease that has a major impact on quality of life (QoL). Objectives: To describe the impact of the different stages of disease in patients with classical mycosis fungoides, folliculotropic mycosis fungoides, and Sézary syndrome on generic- and dermatology-specific QoL and the relation with itch. Methods: A cross-sectional cohort study of patients with classical mycosis fungoides, folliculotropic mycosis fungoides, and Sézary syndrome was performed. Outcomes were the Skindex-29 score, Impact of Chronic Skin Disease on Daily Life which includes a visual analogue scale itch, and RAND-12. Results: One hundred six patients with CTCL were included. Compared to the total mycosis fungoides group, patients with Sézary syndrome had significantly worse Skindex-29 scores. Patients with advanced disease had statistically higher scores for the symptom ( Conclusion: The different stages of CTCL can have a significant effect on multiple domains of generic- and dermatology-specific QoL. Itch was strongly correlated with QoL and therefore can be used as an overall QoL indicator. The effect on QoL, even in patients with early-stage disease, should not be underestimated.

Indexed as

CCI, classic Charlson comorbidity indexcMF, classical MFCTCL, cutaneous T-cell lymphomacutaneous T-cell lymphomaFMF, folliculotropic mycosis fungoidesitchMF, mycosis fungoidesmycosis fungoidesPCS, physical component scoreQol, quality of lifequality of lifeRAND-12Sézary syndromeSkindex-29SS, sézary syndromeSTROBE, Strengthening the Reporting of Observational studies in Epidemiology

Identifiers

PMID36147217
PMCPMC9486110
OpenAlexW4290237559

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.