ArticleJournal of diabetes2022
Temporal trends in patients with peripheral artery disease influenced by diabetes mellitus in Germany.
Article in Journal of diabetes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 5 citations in OpenAlex.
- Impact of type 2 diabetes mellitus on in-hospital outcomes in patients with ST-elevation myocardial infarction: A nationwide study in Germany.Metabolism open · 2026Article
- Clinical and psychological adjustment to prosthesis use in lower-limb amputees: focus on differences between traditional and high-technology rehabilitation.Frontiers in rehabilitation sciences · 2026Article
- Impact of diabetes mellitus on long-term survival after transcatheter mitral valve edge-to-edge repair.International journal of cardiology. Heart & vasculature · 2025Article
- Temporal trends in patients with peripheral artery disease influenced by diabetes mellitus in Germany.Journal of diabetes · 2022Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
introductionIn patients with peripheral artery disease (PAD) the presence of diabetes mellitus (DM) is associated with higher morbidity and mortality. Because huge efforts are made to improve medical care of patients with DM including chronic disease programs, the aim of the present study was to investigate temporal trends regarding the clinical burden of DM on PAD patients within a 15-year observational period.
methodsWe analyzed all patients hospitalized because of PAD between 2005 and 2019 in Germany stratified regarding DM.
resultsOverall, 2 654 871 hospitalizations of PAD patients (865 823 with DM) were included. Hospitalizations based on PAD inclined from 142 778 in 2005 to 190 135 in 2019 (β 3956 per year; 95% confidence interval [CI] 3034-4878, p < .001) with simultaneous increase of hospitalizations of PAD patients with DM (2005: 41609 (29.1%) versus 2019: 65 302 (34.3%); β 2019 per year [95% CI 1593-2446], p < .001). Amputation rates (β -0.42 [95% CI -0.44 to -0.40]; p < .001) as well as in-hospital case-fatality rate (2005: 4.7%, 2019: 2.8%; β -0.64 [95% CI -0.69 to -0.59]; p < .001) decreased in diabetic PAD patients during the observational time. In spite of improved morbidity and mortality in the last years of the observational period, patients with DM still suffered from an increased risk for morbidity and mortality during the observational period compared to nondiabetic PAD patients.
conclusionsDespite the progress in DM treatments, DM still was associated with an unfavorable clinical patient profile and remained a substantial risk factor for morbidity and mortality in hospitalized patients with PAD and DM in Germany between 2005 and 2019.
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