Evidence map›Paper›PMID 36146849›Full record

ArticleViruses2022

SARS-CoV-2 Infection and Pregnancy: Maternal and Neonatal Outcomes and Placental Pathology Correlations.

Michał Pomorski, Martyna Trzeszcz, Agnieszka Matera-Witkiewicz, Magdalena Krupińska, Tomasz Fuchs, Mariusz Zimmer, Aleksandra Zimmer-Stelmach, Anna Rosner-Tenerowicz, Joanna Budny-Wińska, Anna Tarczyńska-Podraza and 20 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Dissecting Rubella Placental Infection in an In Vitro Trophoblast Model.International journal of molecular sciences · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors at 1 institution in 1 country.

Michał PomorskiClinical Department of Gynecology and Obstetrics, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.
Martyna TrzeszczDivision of Pathology and Clinical Cytology, University Hospital in Wroclaw, Borowska Street 213, 50-556 Wroclaw, Poland.ORCID 0000-0002-9971-1093
Agnieszka Matera-WitkiewiczScreening of Biological Activity Assays and Collection of Biological Material Laboratory, Wroclaw Medical University Biobank, Faculty of Pharmacy, Wroclaw Medical University, Borowska Street 211A, 50-556 Wroclaw, Poland.ORCID 0000-0002-1064-1237
Magdalena KrupińskaScreening of Biological Activity Assays and Collection of Biological Material Laboratory, Wroclaw Medical University Biobank, Faculty of Pharmacy, Wroclaw Medical University, Borowska Street 211A, 50-556 Wroclaw, Poland.
Tomasz FuchsClinical Department of Gynecology and Obstetrics, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.
Mariusz ZimmerClinical Department of Gynecology and Obstetrics, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.
Aleksandra Zimmer-StelmachClinical Department of Gynecology and Obstetrics, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.ORCID 0000-0003-1114-6980
Anna Rosner-TenerowiczClinical Department of Gynecology and Obstetrics, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.
Joanna Budny-WińskaClinical Department of Gynecology and Obstetrics, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.
Anna Tarczyńska-PodrazaClinical Department of Gynecology and Obstetrics, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.
Klaudia RadziejewskaClinical Department of Gynecology and Obstetrics, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.ORCID 0000-0001-7680-2083
Barbara Królak-OlejnikDepartment of Neonatology, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.
Anna SzczygiełDepartment of Neonatology, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.
Hanna Augustyniak-BartosikClinical Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.
Magdalena Kuriata-KordekClinical Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.
Karolina SkalecUniversity Hospital in Wroclaw, Borowska Street 213, 50-556 Wroclaw, Poland.
Izabela SmołaClinical Department of Gastroenterology and Hepatology, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.ORCID 0000-0001-8245-1507
Ewa MorgielClinical Department of Rheumatology and Internal Medicine, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.ORCID 0000-0002-9506-698X
Jakub GawryśClinical Department of Internal Medicine, Hypertension and Clinical Oncology, Wroclaw Medical University, Borowska 213, 50-556 Wroclaw, Poland.
Adrian DoroszkoClinical Department of Internal Medicine, Hypertension and Clinical Oncology, Wroclaw Medical University, Borowska 213, 50-556 Wroclaw, Poland.ORCID 0000-0001-5472-028X
Piotr RolaDepartment of Cardiology, Provincial Specialized Hospital, Iwaszkiewicza Street 5, 59-220 Legnica, Poland.ORCID 0000-0002-0963-2712
Małgorzata TrochaDepartment of Pharmacology, Wroclaw Medical University, Mikulicz-Radecki Street 2, 50-345 Wroclaw, Poland.ORCID 0000-0002-3951-205X
Krzysztof KujawaStatistical Analysis Centre, Wroclaw Medical University, K. Marcinkowski Street 2-6, 50-368 Wroclaw, Poland.ORCID 0000-0003-2812-4702
Barbara AdamikClinical Department of Anaesthesiology and Intensive Therapy, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.ORCID 0000-0002-0541-841X
Krzysztof KaliszewskiClinical Department of General, Minimally Invasive and Endocrine Surgery, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.ORCID 0000-0002-3291-5294
Katarzyna Kiliś-PstrusińskaClinical Department of Paediatric Nephrology, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.
Marcin ProtasiewiczClinical Department and Clinic of Cardiology, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.
Janusz SokołowskiDepartment of Emergency Medicine, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.
Ewa A JankowskaInstitute of Heart Diseases, University Hospital, Borowska Street 213, 50-556 Wroclaw, Poland.
Katarzyna MadziarskaClinical Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.ORCID 0000-0002-3624-3691
Wroclaw Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is accumulating evidence on the perinatal aspects of COVID-19, but available data are still insufficient. The reports on perinatal aspects of COVID-19 have been published on a small group of patients. Vertical transmission has been noted. The SARS-CoV-2 genome can be detected in umbilical cord blood and at-term placenta, and the infants demonstrate elevated SARS-CoV-2-specific IgG and IgM antibody levels. In this work, the analysis of clinical characteristics of RT-PCR SARS-CoV-2-positive pregnant women and their infants, along with the placental pathology correlation results, including villous trophoblast immunoexpression status for SARS-CoV-2 antibody, is presented. RT-PCR SARS-CoV-2 amniotic fluid testing was performed. Neonatal surveillance of infection status comprised RT-PCR testing of a nasopharyngeal swab and the measuring of levels of anti-SARS-CoV-2 in blood serum. In the initial study group were 161 pregnant women with positive test results. From that group, women who delivered during the hospital stay were selected for further analysis. Clinical data, laboratory results, placental histomorphology results, and neonatal outcomes were compared in women with immunohistochemistry (IHC)-con SARS-CoV-2-positive and IHC SARS-CoV-2-negative placentas (26 cases). A positive placental immunoprofile was noted in 8% of cases (

Indexed as

COVID-19Pregnancy Complications, InfectiousFemaleHumansImmunoglobulin GImmunoglobulin MInfantInfant, NewbornInfectious Disease Transmission, VerticalPlacentaPregnancySARS-CoV-2Immunoglobulin GImmunoglobulin MCOVID-19maternal and neonatal outcomeplacental pathologypregnancySARS-CoV-2vertical transmission

Identifiers

PMID36146849
PMCPMC9503119
OpenAlexW4296102042

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.