Evidence map›Paper›PMID 36146843›Full record

ReviewViruses2022

Co-Infection and Cancer: Host-Pathogen Interaction between Dendritic Cells and HIV-1, HTLV-1, and Other Oncogenic Viruses.

Tania H Mulherkar, Daniel Joseph Gómez, Grace Sandel, Pooja Jain

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Tania H MulherkarDepartment of Microbiology and Immunology, Drexel University, College of Medicine, 2900 Queen Lane, Philadelphia, PA 19129, USA.
Daniel Joseph GómezDepartment of Microbiology and Immunology, Drexel University, College of Medicine, 2900 Queen Lane, Philadelphia, PA 19129, USA.ORCID 0000-0002-5443-1813
Grace SandelDepartment of Microbiology and Immunology, Drexel University, College of Medicine, 2900 Queen Lane, Philadelphia, PA 19129, USA.
Pooja JainDepartment of Microbiology and Immunology, Drexel University, College of Medicine, 2900 Queen Lane, Philadelphia, PA 19129, USA.ORCID 0000-0001-8057-7835
Drexel University · US

Funding

Pre-clinical testing of a novel immunotherapy for HTLV-induced neurologic diseaseR01NS097147 · NINDS · DREXEL UNIVERSITY · PI JAIN, POOJA · 2017 to 2021
$2.2M
NINDS NIH HHS R01 NS097147
6 · The paper itself

Abstract

Dendritic cells (DCs) function as a link between innate and adaptive immune responses. Retroviruses HIV-1 and HTLV-1 modulate DCs to their advantage and utilize them to propagate infection. Coinfection of HTLV-1 and HIV-1 has implications for cancer malignancies. Both viruses initially infect DCs and propagate the infection to CD4

Indexed as

CoinfectionHIV-1HIV InfectionsHuman T-lymphotropic virus 1NeoplasmsOncogenic VirusesPapillomavirus InfectionsAdultDendritic CellsHIV SeropositivityHost-Pathogen InteractionsHTLV-I InfectionsHumansParaparesis, Tropical Spasticdendritic cellsEBVhepatitis virusesHIV-1HTLV-1infection and canceroncogenic virusestherapeuticsvaccines

Identifiers

PMID36146843
PMCPMC9503663
OpenAlexW4296101511

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.