Evidence map›Paper›PMID 36146734›Full record

ArticleViruses2022

Comparing Current and Next-Generation Humanized Mouse Models for Advancing HIV and HIV/

Madeleine Lepard, Jack X Yang, Sam Afkhami, Aisha Nazli, Anna Zganiacz, Shangguo Tang, Margaret Wa Yan Choi, Fatemah Vahedi, Alexandre Deshiere, Michel J Tremblay and 3 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Applications of humanized mice inMolecular medicine reports · 2026
    Review
  3. Article
  4. Humanized mouse models ofOncoimmunology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Immunopathology of PulmonaryInternational journal of molecular sciences · 2024
    Article
  11. Article
  12. Review
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Madeleine LepardMcMaster Immunology Research Centre, Michael G. DeGroote Institute for Infectious Disease Research, Department of Medicine, McMaster University, Hamilton, ON L8S 4K1, Canada.
Jack X YangMcMaster Immunology Research Centre, Michael G. DeGroote Institute for Infectious Disease Research, Department of Medicine, McMaster University, Hamilton, ON L8S 4K1, Canada.
Sam AfkhamiMcMaster Immunology Research Centre, Michael G. DeGroote Institute for Infectious Disease Research, Department of Medicine, McMaster University, Hamilton, ON L8S 4K1, Canada.
Aisha NazliMcMaster Immunology Research Centre, Michael G. DeGroote Institute for Infectious Disease Research, Department of Medicine, McMaster University, Hamilton, ON L8S 4K1, Canada.ORCID 0000-0001-7410-9963
Anna ZganiaczMcMaster Immunology Research Centre, Michael G. DeGroote Institute for Infectious Disease Research, Department of Medicine, McMaster University, Hamilton, ON L8S 4K1, Canada.
Shangguo TangDepartment of Pathology and Molecular Medicine, McMaster University, Hamilton, ON L8N 3Z5, Canada.
Margaret Wa Yan ChoiMcMaster Immunology Research Centre, Michael G. DeGroote Institute for Infectious Disease Research, Department of Medicine, McMaster University, Hamilton, ON L8S 4K1, Canada.
Fatemah VahediMcMaster Immunology Research Centre, Michael G. DeGroote Institute for Infectious Disease Research, Department of Medicine, McMaster University, Hamilton, ON L8S 4K1, Canada.
Alexandre DeshiereAxe des Maladies Infectieuses et Immunitaires, Centre de Recherche du CHU de Québec-Université Laval, Pavillon CHUL, Québec City, QC G1V 4G2, Canada.
Michel J TremblayAxe des Maladies Infectieuses et Immunitaires, Centre de Recherche du CHU de Québec-Université Laval, Pavillon CHUL, Québec City, QC G1V 4G2, Canada.
Zhou XingMcMaster Immunology Research Centre, Michael G. DeGroote Institute for Infectious Disease Research, Department of Medicine, McMaster University, Hamilton, ON L8S 4K1, Canada.
Charu KaushicMcMaster Immunology Research Centre, Michael G. DeGroote Institute for Infectious Disease Research, Department of Medicine, McMaster University, Hamilton, ON L8S 4K1, Canada.ORCID 0000-0002-7088-2569
Amy GillgrassMcMaster Immunology Research Centre, Michael G. DeGroote Institute for Infectious Disease Research, Department of Medicine, McMaster University, Hamilton, ON L8S 4K1, Canada.
McMaster University · CAUniversité Laval · CA

Funding

CIHR FRN SOP-159229
6 · The paper itself

Abstract

In people living with HIV,

Indexed as

CoinfectionHIV InfectionsMycobacterium tuberculosisTuberculosisAnimalsCD4-Positive T-LymphocytesDisease Models, AnimalHumansMiceHIVhumanized micemouse models of infectious diseaseTB

Identifiers

PMID36146734
PMCPMC9500899
OpenAlexW4293724778

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.