Evidence map›Paper›PMID 36146729›Full record

ArticleViruses2022

Cortical Auditory Evoked Potentials in Children with Prenatal Exposure to Zika Virus.

Laís Cristine Delgado da Hora, Lilian Ferreira Muniz, Leonardo Gleygson Angelo Venâncio, Karina Paes Advíncula, Jéssica Dayane da Silva, Diana Babini Lapa de Albuquerque Britto, Demócrito de Barros Miranda Filho, Elizabeth B Brickley, Ricardo Arraes de Alencar Ximenes, Silvio da Silva Caldas Neto and 1 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Laís Cristine Delgado da HoraDepartment of Speech, Language and Audiology, Universidade Federal de Pernambuco, Recife 50740-520, Brazil.
Lilian Ferreira MunizDepartment of Speech, Language and Audiology, Universidade Federal de Pernambuco, Recife 50740-520, Brazil.
Leonardo Gleygson Angelo VenâncioDepartment of Speech, Language and Audiology, Universidade Federal de Pernambuco, Recife 50740-520, Brazil.ORCID 0000-0002-1971-755X
Karina Paes AdvínculaDepartment of Speech, Language and Audiology, Universidade Federal de Pernambuco, Recife 50740-520, Brazil.
Jéssica Dayane da SilvaGraduate, Program in Human Communication Health, Universidade Federal de Pernambuco, Recife 50740-520, Brazil.
Diana Babini Lapa de Albuquerque BrittoDepartment of Speech, Language and Audiology, Universidade Federal de Pernambuco, Recife 50740-520, Brazil.
Demócrito de Barros Miranda FilhoPós-Graduação em Ciências da Saúde, Universidade de Pernambuco, Recife 50100-010, Brazil.ORCID 0000-0003-2537-1476
Elizabeth B BrickleyDepartment of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London WC1E 7HT, UK.ORCID 0000-0003-0280-2288
Ricardo Arraes de Alencar XimenesPós-Graduação em Ciências da Saúde, Universidade de Pernambuco, Recife 50100-010, Brazil.
Silvio da Silva Caldas NetoDepartment of Surgery, Universidade Federal de Pernambuco, Recife 50740-520, Brazil.
Mariana de Carvalho LealDepartment of Surgery, Universidade Federal de Pernambuco, Recife 50740-520, Brazil.
Universidade Federal de Pernambuco · BRLondon School of Hygiene & Tropical Medicine · GBUniversidade de Pernambuco · BR

Funding

Medical Research Council MC_PC_15088Wellcome TrustWellcome Trust 107779/Z/15/ZWellcome Trust 201870/Z/16/ZWellcome Trust 205377/Z/16/Z
6 · The paper itself

Abstract

Prenatal exposure to ZIKV can cause neurologic and auditory damage. The electrophysiological responses obtained by Cortical Auditory Evoked Potentials (CAEP) may provide an objective method to investigate the function of cortical auditory pathways in children exposed to ZIKV. This case series analyzed the findings of CAEP in prenatal-period ZIKV-exposed children with and without microcephaly. The CAEP was performed in a total of 24 children. Five magnetic resonance imaging (MRI) images of the inner ear and brain of microcephalic children were analyzed and compared with CAEP measurements. Ventriculomegaly (80%), cortical/subcortical calcification (80%), and brain reduction (60%) were the most common alterations in the MRI. The P1-N1-P2 complex of the CAEP was observed in all children evaluated. The peak N2 was absent in two children. In the comparison of the CAEP measurements between the groups, children with microcephaly presented a higher amplitude of P2 (

Indexed as

MicrocephalyPrenatal Exposure Delayed EffectsZika VirusZika Virus InfectionChildEvoked Potentials, AuditoryFemaleHumansPregnancyauditoryauditory cortexchild developmentcongenital infectionCongenital Zika SyndromeelectrophysiologyEvoked PotentialshearingmicrocephalyZika virus

Identifiers

PMID36146729
PMCPMC9502411
OpenAlexW4293728281

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.