Evidence map›Paper›PMID 36146584›Full record

ArticleVaccines2022

Retrospective Cohort Study of COVID-19 in Patients of the Brazilian Public Health System with SARS-CoV-2 Omicron Variant Infection.

Thiago B Murari, Larissa Moraes Dos Santos Fonseca, Hernane B de B Pereira, Aloísio S Nascimento Filho, Hugo Saba, Fulvio A Scorza, Antônio-Carlos G de Almeida, Ethel L N Maciel, José F F Mendes, Tarcísio M Rocha Filho and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Outcomes of Elderly Patients Hospitalized with the SARS-CoV-2 Omicron B.1.1.529 Variant: A Systematic Review.International journal of environmental research and public health · 2023
    Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Thiago B MurariModelagem Computacional, University Center SENAI/CIMATEC, Salvador 41650-010, BA, Brazil.ORCID 0000-0001-5598-2679
Larissa Moraes Dos Santos FonsecaModelagem Computacional, University Center SENAI/CIMATEC, Salvador 41650-010, BA, Brazil.ORCID 0000-0003-4405-1582
Hernane B de B PereiraModelagem Computacional, University Center SENAI/CIMATEC, Salvador 41650-010, BA, Brazil.ORCID 0000-0001-7476-9267
Aloísio S Nascimento FilhoModelagem Computacional, University Center SENAI/CIMATEC, Salvador 41650-010, BA, Brazil.
Hugo SabaModelagem Computacional, University Center SENAI/CIMATEC, Salvador 41650-010, BA, Brazil.ORCID 0000-0001-8402-6416
Fulvio A ScorzaDisciplina de Neurociência, Escola Paulista de Medicina, Universidade Federal de São Paulo (EPM/UNIFESP), São Paulo 04021-001, SP, Brazil.
Antônio-Carlos G de AlmeidaDepartamento de Engenharia de Biossistemas, Universidade Federal de São João del-Rei (UFSJ), São João del-Rei 36307-352, MG, Brazil.ORCID 0000-0003-4893-338X
Ethel L N MacielLaboratório de Epidemiologia, Universidade Federal do Espírito Santo, Vitória 29075-910, ES, Brazil.
José F F MendesDepartamento de Física and I3N, Universidade de Aveiro, 3880 Aveiro, Portugal.ORCID 0000-0002-4707-5945
Tarcísio M Rocha FilhoInternational Center for Condensed Matter Physics and Instituto de Física, Universidade de Brasília, Brasília 70910-900, DF, Brazil.
John R DavidFaculty of Public Health, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
Roberto BadaróModelagem Computacional, University Center SENAI/CIMATEC, Salvador 41650-010, BA, Brazil.ORCID 0000-0002-2861-5061
Bruna Aparecida Souza MachadoModelagem Computacional, University Center SENAI/CIMATEC, Salvador 41650-010, BA, Brazil.
Marcelo A MoretModelagem Computacional, University Center SENAI/CIMATEC, Salvador 41650-010, BA, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several vaccines against COVID-19 are now available, based on different techniques and made by different laboratories spread around the world. With the roll out of the vaccination process in an advanced stage in many countries, the reduced risk of hospitalization due to the Omicron variant relative to the Delta variant infection, despite the higher transmission risk of Omicron, may lead to a misinterpretation of the results, as infection by Omicron is associated with a significant reduction in severe outcomes and shorter hospitalization time than the Delta variant. We compared the in-hospital mortality due to the Omicron (Jan-Mar 2022) with Gamma (Jan 2021) and Delta (Oct-Dec 2021) variants of patients in the Brazilian public health system. This study also discusses the decrease in booster vaccine effectiveness in patients hospitalized due to the Omicron variant compared with the Delta variant. Without a remodeling of vaccines for new variants, booster doses may be necessary with a shorter time interval.

Indexed as

boosterCOVID-19vaccine effectiveness

Identifiers

PMID36146584
PMCPMC9500832

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.